Influence of duration of total breast-feeding on bone mineral density in a Turkish population: does the priority of risk factors differ from society to society?

Date

2006-05-01

Author

Dursun, N
Akın, Serhat
Dursun, E
Sade, I
Korkusuz, F

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

152
views

0
downloads

Introduction: Despite numerous studies on risk factors for osteoporosis the effect of breast-feeding on bone mineral density (BMD) is unclear. In this study our aim was to determine the influence of total duration of breast-feeding on BMD, and subsequent risk of osteoporosis. Methods: A total of 1,486 postmenopausal women over the age of 40 were included in the study. Women with diseases or who were under drug treatments known to affect bone metabolism were excluded. The BMD of the lumbar spine and femoral neck were measured by dual-energy X-ray absorptiometry technique, using either the Norland XA-26 or Lunar DPX-IQ densitometers and were transferred to standard values. Patients were placed in groups of five with respect to the duration of their breast-feeding as never, 1-12 months, 12-24 months, 24-60 months, > 60 months. Results: One-way ANOVA test showed a significant difference between the lumbar spine and femoral neck BMD of these groups of women (p < 0.001, p < 0.001). Post hoc Bonferroni correction revealed that both the lumbar spine and femoral neck BMD results of women with longer duration of total breast-feeding were significantly lower than those of women with less duration of total breast-feeding. In subsequent analysis other potential risk factors were also considered in a multiple linear stepwise regression model. Years since menopause (p < 0.001), weight (p < 0.001), total duration of breast-feeding (p < 0.001), and body mass index (p=0.001) were found to be the most important predictors for lumbar spine BMD; and age (p < 0.001), weight (p < 0.001), years since menopause (p < 0.001), and total duration of breast-feeding (p < 0.001) for femoral neck BMD. Conclusions: This study showed significant associations between total duration of breast-feeding and BMD. In conclusion, total duration of breast-feeding might be an important risk factor besides age, weight, and years since menopause in postmenopausal osteoporosis.

Subject Keywords

Breast-feeding, Osteoporosis, Risk factors

URI

https://hdl.handle.net/11511/40785

Journal

OSTEOPOROSIS INTERNATIONAL

DOI

https://doi.org/10.1007/s00198-005-0029-2

Collections

Department of Petroleum and Natural Gas Engineering, Article

Suggestions

OpenMETU
Core

The effect of hip rotation on bone mineral density of the proximal femur measured by dual energy X-ray absorptiometry Celik, Oezguer; Salci, Yasar; MANİSALI, METİN; Korkusuz, Feza (2009-01-01) Objectives: The aim of this study was to compare the effect of lower extremity position changes on hip bone mineral density measured by dual energy X-ray absorptiometry.
Relationship of Epicardial Adipose Tissue Thickness with Early Indicators of Atherosclerosis and Cardiac Functional Changes in Obese Adolescents with Metabolic Syndrome Bedir, Akyol; Mehmet, Boyraz; Cevriye, Aysoy (Galenos Yayinevi, 2013-9-5) Objective: Epicardial adipose tissue thickness (EATT) is suggested as a new cardiometabolic risk factor. Carotid intima-media thickness (IMT) is a potential indicator of subclinical atherosclerosis in patients with metabolic syndrome (MS). We investigated the association of EATT with carotid IMT and cardiac functional changes in obese adolescents with MS. Methods: One hundred thirty-eight obese adolescents and 63 lean subjects were enrolled in the study. The obese subjects were divided into two subgroups...
Comparison of GST Isoenzyme Expression in Normal and Neoplastic Breast Tissue: Correlation with Clinical and Prognostic Factors OĞUZTÜZÜN, SERPİL; İşcan, Mesude; ÖZHAVZALI, MÜZEYYEN; Sak, Serpil Dizbay (2009-01-01) Glutathione S-transferases in breast tissue play an important role in the susceptibility to the mutagenic effects of chemical carcinogens and in the response of breast tumors to chemotherapy. In this study the immunohistochemical staining characteristics of glutathione S-transferase isoenzymes (alpha, mu, pi, and theta) were investigated in invasive duct carcinomas and in normal breast tissue of 43 patients. The relationships between the expression of the GST isoenzymes and some clinicopathological features...
Effects of ph on human growth hormone production by pichia pastoris considering the expression levels of regulatory genes Bayraktar, Eda; Çalık, Pınar; Department of Chemical Engineering (2009) In this study, the aim was to investigate the effects of pH on therapeutically important protein, recombinant human growth hormone (rhGH), production by Pichia pastoris considering the expression levels of regulatory genes. In this frame, firstly the host microorganism was selected between two different methanol utilization phenotypes of P. pastoris, Mut+ and MutS on media containing glycerol/methanol or sorbitol/methanol. The highest rhGH production, 120 g L-1, and hGH gene expression, 9.84x109 copies mg-1...
Impact of PCB-118 and transformer oil toxicity on anaerobic digestion of sludge: Anaerobic toxicity assay results Kaya, Devrim; İmamoğlu, İpek; Sanin, Faika Dilek (Elsevier BV, 2013-08-01) In this study, possible toxicity of increasing doses of PCB-118 and transformer oil (TO) on anaerobic sludge digestion was investigated. For this purpose, five different sets of reactors were prepared in which four different PCB-118 concentration (1, 10, 20, and 30 mg L-1) and three different TO concentration (0.38, 0.76, and 1.52 g L-1) were applied. Throughout the study, biogas production and composition, pH, TS, VS, and COD as well as PCB concentration were monitored. Toxicity was investigated by anaerob...

Citation Formats

N. Dursun, S. Akın, E. Dursun, I. Sade, and F. Korkusuz, “Influence of duration of total breast-feeding on bone mineral density in a Turkish population: does the priority of risk factors differ from society to society?,” OSTEOPOROSIS INTERNATIONAL, pp. 651–655, 2006, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/40785.