A conducting polymer and a calixarene derivative A novel surface design for glucose detection

2016-07-17
Gökoğlan, Ceren
Söylemez, Saniye
Kesik, Melis
Ünay, Hande
Sayın, Serkan
Çırpan, Ali
Yıldız, Hüseyin Bekir
Toppare, Levent Kamil
In this study, a novel amperometric glucose biosensor based on a conducting polymer and a calixarene was developed. Conducting polymer of (2‐(2‐oc‐tyldodecyl)‐4,7‐di(selenoph‐2‐yl)‐2H‐benzo[d][1,2,3]triazole)) (SBTz) was used as the immobilization matrix for biomolecule deposition to achieve an effective surface design to detect glucose. After successful deposition of SBTz on graphite electrode, a newly synthesized calixarene and gold nanoparticle (AuNP) mixture were used for improving biosensor characteristics. Glucose oxidase (GOx) was immobilized on modified electrode surface. Amperomet‐ric detection was observed at ‐0.7 V vs Ag reference electrode in phosphate buffer solution (50 mM, pH 6.5). Moreover, the constructed biosensor was characterized using scanning electron microscopy (SEM) technique to investi‐gate the surface morphologies. KMapp and sensitivity values were calculated as 0.025 mM and 102 μA/mM cm2, respectively. The proposed biosensor showed a wide linear range between 0.005 mM and 0.5 mM glucose concen‐tration with a low limit of detection (LOD) of 0.004 mM as S/N = 3. Finally, the biosensor was tested for the detection of glucose in beverage samples successfully.
Citation Formats
C. Gökoğlan et al., “A conducting polymer and a calixarene derivative A novel surface design for glucose detection,” presented at the 46th IUPAC World Polymer Congress (MACRO 2016) (17 - 21 Temmuz 2016), 2016, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/85408.