Egsoz gazındaki hidrokarbon, karbon monoksit ve azot oksit (NO) bileşiklerinin üç yollu katalitik konverter ile arıtılması

Date

2014

Author

Önal, Işık
Gerçeker, Duygu
Civan, Aylin

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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In this study, strong magnetic featured silica coated Cobalt ferrite (CoFe204) nanoparticles were labeled with 2-deoxy glucose (2-DG) for better targetting to cancer cells and the molecular effects of these prepared magnetic nanoparticles (MNPs) were investigated in cancer cell lines. In this study, in vitro characterization of 2-DG labelled MNPs were carried out in breast cancer cells (MDA-MB-231 breast cancer and normal cell MCF10A), and cellular uptake mechanisms, genotoxicity, intracellular levels of oxidative stress and stress-related autophagic, apoptotic pathways, mRNA expression profiles of some key genes in different biological pathways were studied. Further development of multifunctional different carrier systems for cancer teraphies with nanotechnological view is one of the popular and privileged area. Thus, the information obtained in this study will contribute to create new therapeutic strategies and to set ground to new studies.

Subject Keywords

Three Way Catalytic Converters, Ceria, Carbon Monoxide Oxidation, Density Functional Theory, Computational Chemistry

URI

https://app.trdizin.gov.tr/publication/project/detail/TVRRNE1qUTA
https://hdl.handle.net/11511/49914

Collections

Department of Chemical Engineering, Project and Design