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Novel conversion of thiols into disulfides, via S-nitrosothiol intermediates using trichloronitromethane

1999-10-15
Demir, Ayhan Sıtkı
Igdir, AC
Mahasneh, AS
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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An efficient oxidative coupling of thiols to give disulfides via thionitrite (S-nitrosothiol) intermediate is described using trichloronitromethane as an efficient reagent in organic solvents and water. Cysteine and glutathione are converted into the corresponding disulfides in water in high yields.
Disulfides, Thionitroso compounds, Thiols, Nitroso compounds
https://hdl.handle.net/11511/56550
Department of Chemistry, Article
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