Novel conversion of thiols into disulfides, via S-nitrosothiol intermediates using trichloronitromethane

Date

1999-10-15

Author

Demir, Ayhan Sıtkı
Igdir, AC
Mahasneh, AS

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An efficient oxidative coupling of thiols to give disulfides via thionitrite (S-nitrosothiol) intermediate is described using trichloronitromethane as an efficient reagent in organic solvents and water. Cysteine and glutathione are converted into the corresponding disulfides in water in high yields.

Subject Keywords

Disulfides, Thionitroso compounds, Thiols, Nitroso compounds

URI

https://hdl.handle.net/11511/56550

Journal

TETRAHEDRON

DOI

https://doi.org/10.1016/s0040-4020(99)00722-x

Collections

Department of Chemistry, Article

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Citation Formats

A. S. Demir, A. Igdir, and A. Mahasneh, “Novel conversion of thiols into disulfides, via S-nitrosothiol intermediates using trichloronitromethane,” TETRAHEDRON, pp. 12399–12404, 1999, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/56550.