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SNX3 (Sorting Nexin 3)
Date
2020-01-01
Author
Çiçek, Esra
Hatil, Ayca Circir
Öyken, Merve
Cingoz, Harun
Erson Bensan, Ayşe Elif
Metadata
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This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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© 2020 Atlas of Genetics and Cytogenetics in Oncology and Haematology.Sorting Nexin 3 (SNX3) gene maps to chromosome 6, minus strand and has 4 exons and 3 introns. There are 3 alternatively spliced isoforms (transcripts). SNX3 is a member of the sorting nexin family. Members of this family generally have BAR domains and phosphoinositide binding regions called the phox (PX) domain, and are involved in intracellular trafficking. Unlike other sorting nexins, SNX3 does not contain a BAR domain. SNX3 protein interacts with phosphatidylinositol-3-phosphates, and is involved in protein trafficking through its role in the retromer complex.
URI
https://hdl.handle.net/11511/57222
Journal
Atlas of Genetics and Cytogenetics in Oncology and Haematology
DOI
https://doi.org/10.4267/2042/70783
Collections
Department of Biology, Article