Synthesis of novel norephedrine-based chiral ligands with multiple stereogenic centers and their application in enantioselective addition of diethylzinc to aldehyde and chalcone

Date

2006-03-06

Author

Unaleroglu, C
Aydin, AE
Demir, Ayhan Sıtkı

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Novel norephedrine-based chiral ligands with multiple stereogenic centers were conveniently prepared from norephedrine and N-substituted pyrrole. These novel chiral ligands were used to catalyze the enantioselective addition of diethylzinc to aldehydes and to chalcone in high yields and with good to high enantioselectivities. The absolute configuration of products was found to be affected by the stereogenic centers on the norephedrine part of the novel chiral ligands.

Subject Keywords

Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Catalysis

URI

https://hdl.handle.net/11511/57885

Journal

TETRAHEDRON-ASYMMETRY

DOI

https://doi.org/10.1016/j.tetasy.2006.02.005

Collections

Department of Chemistry, Article

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Citation Formats

C. Unaleroglu, A. Aydin, and A. S. Demir, “Synthesis of novel norephedrine-based chiral ligands with multiple stereogenic centers and their application in enantioselective addition of diethylzinc to aldehyde and chalcone,” TETRAHEDRON-ASYMMETRY, pp. 742–749, 2006, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57885.