Effects of Formaldehyde Inhalation on Zinc, Copper and Iron Concentrations in Liver and Kidney of Male Rats

Date

2011-05-01

Author

ÖZEN, OĞUZ ASLAN
KUŞ, İLTER
Bakirdere, Sezgin
Sarsilmaz, Mustafa
YAMAN, MEHMET

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

186
views

0
downloads

In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic) and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed that the formaldehyde inhalation caused gradual decline of body weights in the experimental groups when compared with control groups. It was found that subacute (4-week) or subchronic (13-week) exposure to formaldehyde for rats may cause growth retardation. After inhalation procedure, concentration of copper, zinc and iron were determined in liver and kidney tissues of rats using atomic absorption spectrophotometer. In addition, concentrations of Cu, Zn and Fe changed by the effect of formaldehyde in subacute and subchronic groups.

Subject Keywords

Inorganic Chemistry, Clinical Biochemistry, Biochemistry, Endocrinology, Diabetes and Metabolism, Biochemistry, medical, General Medicine

URI

https://hdl.handle.net/11511/68166

Journal

BIOLOGICAL TRACE ELEMENT RESEARCH

DOI

https://doi.org/10.1007/s12011-010-8686-1

Collections

Department of Chemistry, Article

Suggestions

OpenMETU
Core

Effect of cold stress on antioxidant mechanism of winter and spring type barley (hordeum vulgare L.) cultivars Afşar, Nilüfer; Yücel, Ayşe Meral; Department of Biochemistry (2007) In this study, effect of cold stress on physiology and biochemistry of two Turkish barley cultivars, winter type Tarm-92 and spring type Zafer-160, was studied. For chilling stress treatment, cultivars were exposed to +4 ºC for 1, 3 and 7 days, and for freezing stress application acclimated cultivars (+4 ºC for 3 days) were treated with -3 ºC and -7 ºC. After freezing stress treatment, a recovery period was applied for 4 days at 4 ºC. Following analyses were performed on leaf and root tissues: growth parame...
Dietary selenium- and vitamin E-induced alterations in some rabbit tissues Turan, B; Zaloglu, N; Koc, E; Saran, Y; Akkas, N (Springer Science and Business Media LLC, 1997-09-01) The present study was designed to investigate and compare the effects of dietary selenium (Se) and vitamin E on some physiological parameters and histological changes in liver, heart, and skin tissues, as well as the blood parameters and the related enzymes. Both sex young rabbits were fed with deficient (9.8 mu g/kg diet), adequate (225 mu g/kg diet), and rich (4.2 mg/kg diet) Se and vitamin E diets for 12-15 wk for this purpose As the plasma Se levels and the erythrocyte glutathione (GSH) peroxidase activ...
Interactions of cholesterol reducing agent simvastatin with phospholipid model membranes Koçak, Mustafa; Severcan, Feride; Department of Biochemistry (2007) Interactions of simvastatin with zwitterionic dipalmitoyl phosphotidylcholine (DPPC) multilamellar liposomes were investigated as a function of temperature and simvastatin concentration. And acyl chain length effect on the simvastatin-model membrane interactions was monitored with DPPC and dimyristoyl phosphotidylcholine (DMPC) lipids. All studies were carried out by two non-invasive techniques, namely Fourier transform infrared (FTIR) spectroscopy, and differential scanning calorimetry (DSC). The results s...
STUDIES ON METAL RESISTANCE SYSTEM IN KLUYVEROMYCES-MARXIANUS YAZGAN, A; Özcengiz, Gülay; ALAEDDINOGLU, NG (Springer Science and Business Media LLC, 1993-08-01) Through preliminary plate tests, Kluyveromyces marxianus was found to be much more resistant to toxic heavy metals compared to a CUP1R strain of Saccharomyces cerevisiae. Specific growth rate and maximum dry weights affected by increasing metal concentrations were determined to obtain precise patterns of resistance. Metal biosorption was also monitored during the course of growth in synthetic media containing respective metals at 0.5 mM final concentration. Although Zn- and Co-binding was negligible, as muc...
KINETIC-PROPERTIES OF PURIFIED SHEEP LUNG MICROSOMAL NADH-CYTOCHROME B5 REDUCTASE Güray, Nülüfer Tülün (Elsevier BV, 1991-01-01) 1. Lung NADH-cytochrome b5 reductase was saturated with its artificial substrate, potassium ferricyanide at approximately 0.1 mM ferricyanide concentration, and the activity of the lung enzyme was inhibited by the higher concentrations of potassium ferricyanide. Ferricyanide at 0.5 and 1.0 mM inhibited the activity of the enzyme by about 20 and 61% respectively. The apparent K(m) value was calculated as 13.7-mu-M potassium ferricyanide and 4.3-mu-M NADH.

Citation Formats

O. A. ÖZEN, İ. KUŞ, S. Bakirdere, M. Sarsilmaz, and M. YAMAN, “Effects of Formaldehyde Inhalation on Zinc, Copper and Iron Concentrations in Liver and Kidney of Male Rats,” BIOLOGICAL TRACE ELEMENT RESEARCH, pp. 177–185, 2011, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/68166.