STUDIES ON METAL RESISTANCE SYSTEM IN KLUYVEROMYCES-MARXIANUS

Date

1993-08-01

Author

YAZGAN, A
Özcengiz, Gülay
ALAEDDINOGLU, NG

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

208
views

0
downloads

Through preliminary plate tests, Kluyveromyces marxianus was found to be much more resistant to toxic heavy metals compared to a CUP1R strain of Saccharomyces cerevisiae. Specific growth rate and maximum dry weights affected by increasing metal concentrations were determined to obtain precise patterns of resistance. Metal biosorption was also monitored during the course of growth in synthetic media containing respective metals at 0.5 mM final concentration. Although Zn- and Co-binding was negligible, as much as 90% of silver, 60% of copper, and 65% of cadmium were found to be absorbed by the end of active growth. Analysis of the protein profiles of S. cerevisiae and K. marxianus on metal exposure suggested constitutive production of metallothionein in K. marxianus. Furthermore, a smaller protein synthesized by K. marxianus on induction by silver or cadmium accounts for the high resistance of the organism to these metals.

Subject Keywords

Inorganic Chemistry, Clinical Biochemistry, Biochemistry, Endocrinology, Diabetes and Metabolism, Biochemistry, medical, General Medicine

URI

https://hdl.handle.net/11511/38981

Journal

BIOLOGICAL TRACE ELEMENT RESEARCH

DOI

https://doi.org/10.1007/bf02784048

Collections

Department of Biology, Article

Suggestions

OpenMETU
Core

Dietary selenium- and vitamin E-induced alterations in some rabbit tissues Turan, B; Zaloglu, N; Koc, E; Saran, Y; Akkas, N (Springer Science and Business Media LLC, 1997-09-01) The present study was designed to investigate and compare the effects of dietary selenium (Se) and vitamin E on some physiological parameters and histological changes in liver, heart, and skin tissues, as well as the blood parameters and the related enzymes. Both sex young rabbits were fed with deficient (9.8 mu g/kg diet), adequate (225 mu g/kg diet), and rich (4.2 mg/kg diet) Se and vitamin E diets for 12-15 wk for this purpose As the plasma Se levels and the erythrocyte glutathione (GSH) peroxidase activ...
Effects of Formaldehyde Inhalation on Zinc, Copper and Iron Concentrations in Liver and Kidney of Male Rats ÖZEN, OĞUZ ASLAN; KUŞ, İLTER; Bakirdere, Sezgin; Sarsilmaz, Mustafa; YAMAN, MEHMET (Springer Science and Business Media LLC, 2011-05-01) In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic) and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed that the formaldehyde inhalation caused gradual decline of body weights in the experimental groups when compared with control groups. It was found that subacute (4-week) or subchronic (13-week) exposure to formaldehyde for rats may cause growth retardation...
Examination of the dielectrophoretic spectra of MCF7 breast cancer cells and leukocytes Çağlayan, Zeynep; Demircan Yalçın, Yağmur; Külah, Haluk (Wiley, 2020-03-01) The detection of circulating tumor cells (CTCs) in blood is crucial to assess metastatic progression and to guide therapy. Dielectrophoresis (DEP) is a powerful cell surface marker-free method that allows intrinsic dielectric properties of suspended cells to be exploited for CTC enrichment/isolation from blood. Design of a successful DEP-based CTC enrichment/isolation system requires that the DEP response of the targeted particles should accurately be known. This paper presents a DEP spectrum method to inve...
Determination of Zinc, Copper, Iron, and Manganese in Different Regions of Lamb Brain Bakirdere, Sezgin; Kizilkan, Nese; YAMAN, MEHMET (Springer Science and Business Media LLC, 2011-09-01) The levels of zinc, copper, iron, and manganese were measured in the hippocampus, thalamus, gyrus cinguli, hypothalamus, and in the prefrontal, parietal, temporal, and occipital cortexes of lamb brain by flame atomic absorption spectrometry. Standard addition method was also applied to samples and it was observed that there was no matrix interference affecting the determination of elements interested. In the determination of Cu, a slotted tube atom trap was used to improve sensitivity. One-way analysis of v...
The Effect of Boron-Containing Nano-Hydroxyapatite on Bone Cells Gizer, Merve; Kose, Sevil; KARAOSMANOĞLU, BEREN; Taskiran, Ekim Z.; BERKKAN, AYSEL; Timucin, Muharrem; Korkusuz, Feza; KORKUSUZ, PETEK (Springer Science and Business Media LLC, 2020-02-01) Metabolic diseases or injuries damage bone structure and self-renewal capacity. Trace elements and hydroxyapatite crystals are important in the development of biomaterials to support the renewal of bone extracellular matrix. In this study, it was assumed that the boron-loaded nanometer-sized hydroxyapatite composite supports the construction of extracellular matrix by controlled boron release in order to prevent its toxic effect. In this context, boron release from nanometer-sized hydroxyapatite was calcula...

Citation Formats

A. YAZGAN, G. Özcengiz, and N. ALAEDDINOGLU, “STUDIES ON METAL RESISTANCE SYSTEM IN KLUYVEROMYCES-MARXIANUS,” BIOLOGICAL TRACE ELEMENT RESEARCH, pp. 117–127, 1993, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/38981.