Impact of UV treatment for the removal of bacterial genes during wastewater treatment

Bulut, Taliye
İçgen, Bülent
Wastewater treatment plants (WWTPs) are considered as important hotspots for the spread of the antibiotic resistance genes (ARGs). The dissemination of ARGs is one of the most significant threat to public health. This also causes a danger for water quality in surface waters and groundwater. These waters can easily be included in human life by their use in places such as agriculture, livestock and drinking waters. The bacterial gene is important to analyze the quantity of the total bacterial load and to normalize the abundance of ARGs in the collected samples. While WWTP design has been mastered for the removal of solids, organic matter, and nutrients, they have not been intentionally designed for removal of micropollutants and pathogenic microorganisms. Therefore, in this study, removal efficiencies of these bacterial genes was investigated through UV treatment units in WWTP.
International Ecology Symposium, (19 - 23 Haziran 2018)


Impact of wastewater treatment plants on dissemination of antibiotic resistance genes
Küçükünsal, Serkan; İçgen, Bülent; Department of Environmental Engineering (2019)
Wastewater treatment plants (WWTPs) as hotspots of the antibiotic resistance genes (ARGs) pose risk to receiving environments. Removal of ARGs through WWTPs, therefore, is great importance. For this reason, common types of WWTPs including conventional activated sludge (CAS), biological nutrient removal (BNR), sequencing batch reactor (SBR), membrane bioreactor (MBR), package MBR, WWTP with coagulation-flocculation and UV disinfection units were investigated in terms of their seasonal removal efficiencies on...
Effect of UV treatment for the removal of sulfonamide resistance gene during wastewater treatment
Bulut, Taliye; İçgen, Bülent (2018-04-27)
The dissemination of the antibiotic resistance genes (ARGs) is considered as one of the most important threats to public health. This dissemination also becomes a threat for water quality in surface waters and groundwater. Waters contaminated with ARGs can easily be incorporated into human life through several ways like drinking water, agriculture and animal husbandry. Sulfonamide resistance gene, one of the ARGs, in discharged waters increases gradually because the use of these drugs is highly common. Wast...
Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes
Welch, KT; Virga, KG; Whittemore, NA; Özen, Can; Wright, E; Brown, CL; Lee, RE; Serpersu, EH (2005-11-15)
Chemical modification and inactivation of aminoglycosides by many different enzymes expressed in pathogenic bacteria are the main mechanisms of bacterial resistance to these antibiotics. In this work, we designed inhibitors that contain the 1,3-diamine pharmacophore shared by all aminoglycoside antibiotics that contain the 2-deoxystreptamine ring. A discovery library of molecules was prepared by attaching different side chains to both sides of the 1,3-diamine motif. Several of these diamines showed inhibito...
Impact of different environmental conditions on the aggregation of biogenic U(IV) nanoparticles synthesized by Desulfovibrio alaskensis G20
Şengör, Sema Sevinç; Dohnalkova, Alice; Spycher, Nicolas; Ginn, Timothy R.; Peyton, Brent M.; Sani, Rajesh K. (2016-12-01)
This study investigates the impact of specific environmental conditions on the formation of colloidal U(IV) nanoparticles by the sulfate reducing bacteria (SRB, Desulfovibrio alaskensis G20). The reduction of soluble U(VI) to less soluble U(IV) was quantitatively investigated under growth and non-growth conditions in bicarbonate or 1,4-piperazinediethanesulfonic acid (PIPES) buffered environments. The results showed that under non-growth conditions, the majority of the reduced U nanoparticles aggregated and...
The effects of palbociclib on 2d and 3d cell cultures and doxorubicin resistance
Yalçın, Gizem Damla; Gündüz, Ufuk; Department of Molecular Biology and Genetics (2020)
Cell culture facilitates studying the mechanism of diseases and finding new treatment strategies. Traditionally used two­dimensional cell culture model is not quite sufficient in some studies due to the factors such as lack of cell to cell and cell­extracellular matrix interactions and changing cell morphology. Because of the limitations in 2D cell culture, nowadays three­dimensional cell cultures gain importance. The present study aims to identify the effect of Palbociclib on different cells when they cult...
Citation Formats
T. Bulut and B. İçgen, “Impact of UV treatment for the removal of bacterial genes during wastewater treatment,” presented at the International Ecology Symposium, (19 - 23 Haziran 2018), Kastamonu, Türkiye, 2018, Accessed: 00, 2021. [Online]. Available: