Mitochondrial dna (mtdna) sequence analyses of Kangal Dogs in Turkey

Gökçek, Çiğdem
Kangal dogs are the most popular dogs of Turkey due to their strength, intelligence, loyalty, endurance to extreme temperatures and their lack of predatory behavior towards livestock. In this study to provide genetic information about the distinctness of Kangal and Akbash dogs and hence to provide a basis to conserve them separately, 585 base pair of the mitochondrial DNA (mtDNA) control region sequence was analysed in 105 Kangal and 9 Akbash dog samples. All the results indicated that Kangal and Akbash dogs were different from each other. Comparison of the Turkish data with those from other dogs revealed that Kangal dogs harbour a rare haplogroup which is only seen in Scandinavian (36%), Portuguese (20%), Turkish (20%) dogs and only one Spanish dog, but not in Akbash, Middle Eastern, other European, Eastern Asian and Indian dogs. Furthermore, comparison of the Kangal and Akbash dogs with the dogs from different geographic regions indicated that Kangal dogs are genetically closer to Scandinavian and South West Asian dogs whereas Akbash dogs are more similar to European and East Asian dogs, based on the mtDNA control region sequences Today, the sizes of Kangal and especially Akbash populations are decreasing. An urgent program for their conservation is needed. In order to conserve them separately, it must be understood that these two dogs are genetically distinct. That is why, the main purpose of the present study is to provide genetic information about the distinctness of Kangal and Akbash dogs.


Polymorphism of Prolactin (PRL), Diacylglycerol Acyltransferase (DGAT-1) and Bovine Solute Carrier Family 35 Member 3 (SLC35A3) genes in native cattle breeds and its implication for Turkish cattle breeding
Kepenek, Eda Şeyma; Togan, İnci Zehra; Department of Biology (2007)
In the present study samples from four native Turkish Cattle Breeds; South Anatolian Red (n= 48), East Anatolian Red (n= 34), Anatolian Black (n= 42) and Turkish Grey (n=46) and elite bulls of Holstein (n=21) were genotyped with respect to two milk production enhancer genes, Prolactin (PRL) and Diacylglycerol acyltransferase (DGAT1), and one disease (Complex Vertebral Malformation) causing gene (SLC35A3). A allele frequency for PRL gene, believed to be positively associated with the milk yield in cattle, ra...
Genetic diversity of native and crossbreed sheep breeds in Anatolia
Koban, Evren; Togan, İnci Zehra; Department of Biology (2004)
In this study the genetic diversity in Turkish native sheep breeds was investigated based on microsatellite DNA loci. In total, 423 samples from 11 native and crossbreed Turkish sheep breeds (Akkaraman, Morkaraman, Kivircik, Ivesi, Dagliç, Karayaka, Hemsin, Norduz, Kangal, Konya Merinosu, Türkgeldi) and one Iraqi breed (Hamdani) were analyzed by sampling from breeding farms and local breeders. After excluding close relatives by Kinship analysis, the genetic variation within breeds was estimated as gene dive...
Genetic evidence for the distinctness of Kangal dogs
Altunok, V; Koban, E; Chikhi, L; Schaffer, A; Pedersen, NC; Nizamlioglu, M; Togan, İnci Zehra (2005-01-01)
The genetic diversity of Kangal dogs (n=23) was analysed using 100 canine microsatellites, and the results were compared to Central Anatolian feral dogs (n=51), Akbash dogs (n=6), and Turkish greyhounds (TG, n=3). The Kangal, Akbash, Turkish greyhound and feral dogs were found to be significantly different from each other by F-ST measure. Factorial Correspondence Analysis (FCA), which evaluated the span of genotypic variation between individual dogs, yielded 4 distinct groups of the animals. Group I was com...
Population Genomics Reveal Recent Speciation and Rapid Evolutionary Adaptation in Polar Bears
Liu, Shiping; et. al. (Elsevier BV, 2014-05-08)
Polar bears are uniquely adapted to life in the High Arctic and have undergone drastic physiological changes in response to Arctic climates and a hyper-lipid diet of primarily marine mammal prey. We analyzed 89 complete genomes of polar bear and brown bear using population genomic modeling and show that the species diverged only 479-343 thousand years BP. We find that genes on the polar bear lineage have been under stronger positive selection than in brown bears; nine of the top 16 genes under strong positi...
Türkiye’den 12 Yerli, Karagül, Karacabey Merinosu ve Anadolu Yaban Koyununda (Ovis gmelinii anatolica) Y-Kromozom Polimorfizmleri
PARMAKSIZ, Arif; OYMAK, Ahmet; YÜNCÜ, Eren; DEMİRCİ, Sevgin; KOBAN BAŞTANLAR, Evren; ÖZKAN ÜNAL, Emel; TOGAN, İnci; ÖZER, Füsun (Kafkas University, 2018)
In this study, 182 male animals from 12 native sheep breeds, as well as Karacabey Merino and Karagül breeds of Anatolia, wild sheep Anatolian Mouflon (Ovis gmelinii anatolica) were used as the study material. Based on SRY and SRYM18 regions on the Y-chromosome, haplotypes of the populations were analyzed using DNA sequence analyses. The SRY region, A-oY1 allele was observed in all of the individuals studied. On the other hand, four different alleles corresponding to four Y-chromosome haplotypes were dete...
Citation Formats
Ç. Gökçek, “Mitochondrial dna (mtdna) sequence analyses of Kangal Dogs in Turkey,” M.S. - Master of Science, Middle East Technical University, 2005.