Hydrogen-Bonded Multilayers With Controllable pH-Induced Disintegration Kinetics for Controlled Release Applications From Surfaces

Date

2015-04-03

Author

Bağ, Esra
Begik, Oguzhan
Yusan, Pelin
Erel Göktepe, İrem

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

98
views

0
downloads

We report on incorporation of coordination complexes into hydrogen-bonded multilayers which was found to be an effective method to control pH-induced disintegration kinetics of hydrogen-bonded multilayers. By taking advantage of the strong metal chelating and hydrogen donating properties of Tannic Acid (TA), coordination complexes of Zr4+ and TA (Zr(IV)-TA complexes) were prepared and then self-assembled at the surface using hydrogen accepting polymers such as poly (N-vinyl caprolactam) (PVCL) or poly(N-isopropyl acrylamide) (PNIPAM). Incorporation of Zr(IV)-TA complexes into hydrogen-bonded multilayers allowed controlling kinetics of pH-induced disintegration of the films. We found that the onset of pH-triggered disintegration of the multilayers could be delayed for similar to 10h at a physiologically related pH, which may be an important feature for controlled delivery applications from surfaces. In contrast to neutral polymer/TA multilayers which dissolve rapidly above their critical pH, multilayers of Zr(IV)-TA complexes dissolved in a linear fashion in a longer period of time than that of multilayers composed solely from hydrogen bonding polymers. Multilayers of Zr(IV)-TA complexes could uptake methylene blue at a moderately acidic pH and release the dye molecules at strongly acidic conditions. This study contributes to fundamental understanding of structure-property relationship in hydrogen-bonded LbL films. Considering the interesting biological properties of TA, multilayers of Zr(IV)-TA complexes may be promising for future biomedical applications.

Subject Keywords

pH-triggered release, Layer-by-layer, pH-responsive, Hydrogen-bonded multilayers

URI

https://hdl.handle.net/11511/40680

Journal

JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY

DOI

https://doi.org/10.1080/10601325.2015.1007274

Collections

Department of Chemistry, Article

Suggestions

OpenMETU
Core

Hydrogen generation from the methanolysis of ammonia borane catalyzed by in situ generated, polymer stabilized ruthenium(0) nanoclusters Erdogan, Huriye; Metin, Onder; Özkar, Saim (2011-07-19) Addressed herein is the detailed study on in situ generation of poly(N-vinyl-2-pyrrolidone) (PVP) stabilized ruthenium(0) nanoclusters and their catalysis in the methanolysis of ammonia borane (AB). PVP-stabilized ruthenium(0) nanoclusters with an average particle size of 2.4 +/- 1.2 nm were generated in situ from the reduction of ruthenium(III) chloride during the methanolysis of AB in the presence of PVP at room temperature. The nanoclusters were characterized by UV-vis spectroscopy, TEM, XRD, XPS and FTI...
Polymer-immobilized palladium supported on TiO2 (Pd-PVB-TiO2) as highly active and reusable catalyst for hydrogen generation from the hydrolysis of unstirred ammonia-borane solution Rakap, Murat; Kalu, Egwu Eric; Özkar, Saim (Elsevier BV, 2011-01-01) Herein we report the preparation, characterization and the catalytic use of the polymer-immobilized palladium catalyst supported on TiO2 (Pd-PVB-TiO2) in the hydrolysis of unstirred ammonia-borane solution. The polymer-immobilized palladium catalyst is stable enough to be isolated as solid materials and characterized by XRD, SM, and EDX. The immobilized palladium catalyst supported on TiO2 is found highly active, isolable, and reusable in the hydrolysis of unstirred ammonia-borane even at low concentrations...
Sulfur capture for fluidized-bed combustion of high-sulfur content lignites Altindag, H; Gogebakan, Y; Selçuk, Nevin (2004-12-01) Sulfur release and capture behavior of lignites with highly combustible sulfur-contents were investigated by extending a previously-developed comprehensive model to incorporate sulfur retention. The predictive performance of the model was tested by comparing the model predictions with on-line concentration measurements of O-2, CO2, CO and SO2. Favorable comparisons are obtained between the predicted and measured concentrations of gaseous species along the combustor. Results show that freeboard sulfur-captur...
Temperature-dependent radiative lifetimes of excitons in non-polar GaN/AlGaN quantum wells Rudin, S.; Garrett, G. A.; Shen, H.; Wraback, M.; İmer, Muhsine Bilge; Haskell, B.; Speck, J. S.; Keller, S.; Nakamura, S.; DenBaars, S. P. (2007-01-01) We report theoretical and experimental studies of radiative recombination of carriers in GaN quantum wells grown on low defect a-plane GaN templates fabricated by lateral epitaxial overgrowth. The radiative rates are presented as functions of temperature and well width.
Hydrogen generation from the hydrolysis of hydrazine-borane catalyzed by rhodium(0) nanoparticles supported on hydroxyapatite Celik, Derya; Karahan, Senem; Zahmakiran, Mehmet; Özkar, Saim (2012-03-01) Herein, we report the preparation and characterization of rhodium(0) nanoparticles supported on hydroxyapatite (Ca-10(OH)(2)(PO4)(6), HAP) and their catalytic use in the hydrolysis of hydrazine-borane, which attracts recent attention as promising hydrogen storage materials. Hydroxyapatite supported rhodium(0) nanoparticles were readily prepared by the hydrazine-borane reduction of rhodium(III)-exchanged hydroxyapatite in situ during the hydrolysis of hydrazine-borane at room temperature. Characterization of...

Citation Formats

E. Bağ, O. Begik, P. Yusan, and İ. Erel Göktepe, “Hydrogen-Bonded Multilayers With Controllable pH-Induced Disintegration Kinetics for Controlled Release Applications From Surfaces,” JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, pp. 286–298, 2015, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/40680.