Calcium Phosphate Mineralization on Calcium Carbonate Particle Incorporated Silk-Fibroin Composites

Download

index.pdf

Date

2019-09-01

Author

Kapusuz, Derya
Ercan, Batur

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

64
views

0
downloads

In this study, three anhydrous forms of calcium carbonate, namely vaterite, aragonite and calcite, with distinct morphologies were incorporated inside silk-fibroin to fabricate composite scaffolds for tissue engineering applications. To assess calcium phosphate mineralization, composite scaffolds were treated with simulated body fluid up to one month. It was observed that composite scaffolds having different calcium carbonate polymorphs expressed different mineralization. Incorporating 25 wt. % of vaterite polymorph, which was the least stable form of calcium carbonate under aqueous conditions, induced the highest calcium phosphate mineralization in silk-fibroin while calcium carbonate-free silk-fibroin scaffolds expressed no calcium phosphate deposition. Results highlighted the importance of calcium carbonate particles in enhancing the bioactivity of silk-fibroin based composite scaffolds

Subject Keywords

Bioactivity, Calcium carbonate, Composite, Silk-fibroin, Simulated body fluid

URI

https://hdl.handle.net/11511/46380

Journal

Celal Bayar Üniversitesi Fen Bilimleri Dergisi

DOI

https://doi.org/10.18466/cbayarfbe.573625

Collections

Department of Metallurgical and Materials Engineering, Article

Suggestions

OpenMETU
Core

Thermal degradation of polysiloxane and polyetherester containing benzoxazine moieties in the main chain Bagherifam, Shahla; Kışkan, Barış; Aydogan, Binnur; Yagci, Yusuf; Hacaloğlu, Jale (2011-01-01) In this study investigation of thermal characteristics of polysiloxane and polyetherester containing benzoxazine moieties in the main chain was performed via pyrolysis mass spectrometry. Pyrolysis mass spectrometry analyses revealed that the thermal stability and the extent of cross-linking enhanced when the benzoxazine moieties were separated by thermally more stable units such as siloxanes. However, when the siloxane chain units were long, possibility of polybenzoxazine growth decreased significantly and ...
Synthesis of biomimetic Ca-hydroxyapatite powders at 37 degrees C in synthetic body fluids Tas, AC (2000-07-01) An important inorganic phase for synthetic bone applications, calcium hydroxyapatite (HA, Ca-10(PO4)(6)(OH)(2)), was prepared as a nano-sized (similar to 50 nm), homogeneous and high-purity ceramic powder from calcium nitrate tetrahydrate and diammonium hydrogen phosphate salts dissolved in modified synthetic body fluid (SBF) solutions at 37 degrees C and pH of 7.4 using a novel chemical precipitation technique. The synthesized precursors were found to easily reach a phase purity >99% after 6 h of calcinati...
Synthesis of calcium carbonate particles for biomedical applications Oral, Çağatay Mert; Ercan, Batur; Department of Metallurgical and Materials Engineering (2020) Calcium carbonate (CaCO3) particles have been widely used in biomedical applications owing to their biocompatibility and biodegradability. In order to effectively utilize CaCO3 particles in biomedical applications, their physical and chemical properties should be systematically controlled. However, this is a challenging task due to the presence of three different anhydrous CaCO3 polymorphs having complex crystallization behavior. In this thesis, CaCO3 particles were synthesized at distinct environments to c...
Thermal degradation of Polylactide/Poly(ethylene glycol) fibers and composite fibers involving organoclay Ozdemir, Esra; Hacaloğlu, Jale (2018-01-01) In this study, electrospun fibers of melt blended poly(lactic acid) and poly(ethylene glycol), (PLA)-PEG blends involving 10, 15 and 20 wt% PEG and their corresponding composites with organically modified montmorillonite, Cloisite 30B were prepared and characterized by x-ray diffraction, differential scanning calorimetry, thermogravimetry and direct pyrolysis mass spectrometry techniques. The narrower fiber diameters observed for the PLA-PEG fibers involving organoclay compared to the corresponding neat fib...
Surface characteristics and in-vitro behavior of chemically treated bulk Ti6Al7Nb alloys ESEN, ZİYA; Ocal, Ezgi Butev (2017-01-15) The effect of various treatments on surface chemical composition and structure, and bioactivity of Ti6Al7Nb bulk alloys has been investigated. The alloys were treated employing aqueous solutions of NaOH and CaCl2 separately, and also by subsequent CaCl2 treatment after NaOH treatment (NaOH-CaCl2 treatment) which were followed by heat treatment. NaOH treatment was observed to be effective in enrichment of surface layer with Na. On the other hand, Na+ ions were mostly replaced by Ca2+ ions as a result of NaOH...

Citation Formats

D. Kapusuz and B. Ercan, “Calcium Phosphate Mineralization on Calcium Carbonate Particle Incorporated Silk-Fibroin Composites,” Celal Bayar Üniversitesi Fen Bilimleri Dergisi, pp. 301–306, 2019, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/46380.