Salman, Hüseyin Enes
Yazıcıoğlu, Yiğit
Arterial stenosis leads to serious health problems such as stroke and heart attack. For a clinician, it is of critical importance to diagnose the stenosis at an early stage to prevent serious damage. Peripheral artery diseases observed in the arms and legs can be a sign of serious cardiovascular disorders. For a stenosed artery, turbulence is observed downstream of constriction exit. Turbulent flow generates sound and vibration on artery wall. Vibro-acoustic radiation propagates through surrounding tissues and reaches skin surface. In this study, skin surface response of thigh due to acoustic generation from a stenosed femoral artery is investigated which may provide important information for diagnostic purposes. Human thigh is modelled using commercial finite element analysis software ADINA. Modal analyses are performed for thigh model. Realistic material properties and model geometry are employed. Acoustic generation due to arterial stenosis is modelled using empirical relations provided in literature. Harmonic acoustic pressures are applied on the inner surface of the artery wall. Radial velocity response and pressure response on thigh skin surface are obtained by considering different stenosis degrees and different stenosis locations. Results indicate that increasing stenosis degree leads to an increase in amplitudes of harmonic responses. Highest radial velocity and pressure amplitudes are obtained at locations closest to the arterial stenosis. Low frequency response between 0-50 Hz is found to be more useful to obtain information about the location of the stenosis.


Flow-induced vibration analysis of constricted artery models with surrounding soft tissue
Salman, Huseyin Enes; Yazıcıoğlu, Yiğit (2017-10-01)
Arterial stenosis is a vascular pathology which leads to serious cardiovascular diseases. Blood flow through a constriction generates sound and vibration due to fluctuating turbulent pressures. Generated vibro-acoustic waves propagate through surrounding soft tissues and reach the skin surface and may provide valuable insight for noninvasive diagnostic purposes. Motivated by the aforementioned phenomena, vibration of constricted arteries is investigated employing computational models. The flow-induced press...
Risk analysis based on spatial analysis of chronic obstructive pulmonary disease (COPD) with respect to provinces in Turkey
Ciftci, Sezgin; Duzgun, Sebnem; Başbuğ Erkan, Berna Burçak (2014-03-15)
The goal of this study is to analyze and understand the risks of chronic obstructive pulmonary disease (COPD) with respect to the provinces of Turkey according to the results of spatial analysis.
Comparison of five regularization methods for the inverse electrocardiography problem
Güçlü, Alperen; Serinağaoğlu Doğrusöz, Yeşim; Department of Electrical and Electronics Engineering (2013)
Understanding heart’s electrical activity is very important because coronary problems -such as heart attacks, arrhythmia and stroke- are the leading cause of death in the world. Forward and inverse problems of electrocardiography (ECG) are methods that provide detailed information about the electrical activity of the heart. Forward problem of electrocardiography is the estimation of body surface potentials from equivalent cardiac sources. Inverse problem of electrocardiography can be described as estimation...
Human serum arylesterase and glutathione s-transferase activities in patients with ischemic stroke compared to healthy controls
Türkanoğlu, Aysun; Adalı, Orhan; Department of Biochemistry (2007)
Stroke is an important public health problem and the third leading cause of death after coronary heart diesase and all cancers in all over the world. Free radicals and oxidative stress play important role in the pathogenesis of several diseases including atherosclerosis, stroke, cancer, neurodegenerative diseases such as Alzheimer's dementia. The activity of paraoxonase (PON1) aganist phenylacetate is known as arylesterase (ARE). Paraoxonase is an esterase associated with high-density lipoprotein (HDL) and ...
Investigation of on skin surface response due to acoustic radiation from stenosed blood vessels
Salman, Huseyin E.; Yazıcıoğlu, Yiğit (2015-11-02)
Arterial stenosis is a form of cardiovascular disease which leads to highest rate of fatalities worldwide. When stenosis is present in coronary arteries, it leads to heart attack and often sudden death. Arterial disease is usually not confined to critical organs such as the heart and the brain but observed throughout the peripheral cardiovascular system. When an artery has a diameter reduction, acoustic radiation originating from this constriction propagates through soft tissues and reaches to skin surface....
Citation Formats
H. E. Salman and Y. Yazıcıoğlu, “SKIN SURFACE RESPONSE DUE TO ACOUSTIC RADIATION FROM STENOSED FEMORAL ARTERY,” presented at the 23rd International Congress on Sound and Vibration (ICSV), Athens, GREECE, 2016, Accessed: 00, 2020. [Online]. Available: