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2-(İyodometilen)-2,3-dihidro-1,4-oksazepin Türevlerinin N-Proparjilik β-Enaminon Bileşiklerinden Sentezi
Date
2017-04-02
Author
Dikmen, Ezel
Kelgökmen, Yılmaz
Zora, Metin
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URI
https://hdl.handle.net/11511/88015
https://ilackongresi.org/arsiv/5-ilac-kongresi/#
Conference Name
5. İlaç Kimyası Kongresi, 30 Mart - 02 Nisan 2017
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Department of Chemistry, Conference / Seminar
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2,3-Dihidro-1,4-oksazepin Türevlerinin N-Proparjilik β-EnaminonBileşiklerinden Sentezi
Kelgökmen, Yılmaz; Çayan, Yasemin; Zora, Metin (null; 2017-04-02)
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Üçlü DNA sarmal yapılarının önemi bu yapıların anti-gen stratejilerinde kullanılabilceğinin ortaya çıkması ile önem kazanmıştır. Anti-gen stratejilerindeki temel hedeflerden ilki üçüncü bir dizinin DNA ikili sarmlarına bağlanarak üçlü sarmal yapı oluşturması ve bu şekilde transkripte görev alan proteinlerin, polimerazların vb. gene bağlanmalarının engellemesidir. Anti-gen stratejilerindeki sorunlardan birisi ise genelde oluşturulan üçlü sarmal yapıların yeterince stabile (sağlam) olmamalarından dolayı ikil...
Chemoenzymatic synthesis of 2-ethyl-5-hydroxy-3- methoxy-cyclopent-2-enone
Dalfidan, Çağla; Demir, Ayhan Sıtkı; Department of Chemistry (2005)
Chiral hydroxylated cyclopentane derivatives are important precursors for biologically active compounds. Synthesis of these types of compounds in optically pure form found increased interest in pharmaceutical chemistry. 2-ethyl-cyclopentane-1.3-dione was acetoxylated using manganese III acetate at preferred positions. Enzyme catalyzed enantioselective hydrolysis or enantioselective acetoxylation of hydrolyzed acetoxy derivatives gives the corresponding hydroxylated diketones in optically pure form.
2 AminoDMAP ve Kinin Temelli Bifonksiyonel Organokatalizörler ile 1 Nitropropanın Nitroolefinlere Enantiyoseçici Michael Katılması
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Polymerization and characterization of 2-Hydroxyethyl acrylate
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Poly(2-Hydroxyethyl acrylate), PHEA, is used as hydrophilic polymeric gels which have been studied because of its great importance for agricultural or biomedical applications. Biomedical applications of hydrogels include soft contact lenses, artificial corneas, soft tissue substitutes and burn dressings. In this study, it was aimed to synthesis the polymers with well-defined molecular weights, polydispersities and cahin topologies. Bulk, solution and atom transfer radical polymerization (ATRP) techniques at...
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E. Dikmen, Y. Kelgökmen, and M. Zora, “2-(İyodometilen)-2,3-dihidro-1,4-oksazepin Türevlerinin N-Proparjilik β-Enaminon Bileşiklerinden Sentezi,” Antalya, Türkiye, 2017, vol. 2017, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/88015.