Department of Chemistry

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Toppare, Levent Kamil (450)
Özkar, Saim (284)
Türker, Burhan Lemi (216)
Çırpan, Ali (138)
Tanyeli, Cihangir (135)

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Materials Chemistry (349)
Organic Chemistry (349)
Polymers and Plastics (285)
General Chemistry (273)
Physical and Theoretical Chemistry (253)

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1960 - 1979 (152)
1980 - 1999 (904)
2000 - 2019 (2688)
2020 - 2021 (106)

Recent Submissions

Cobalt ferrite supported platinum nanoparticles: Superb catalytic activity and outstanding reusability in hydrogen generation from the hydrolysis of ammonia borane
Akbayrak, Serdar; Özkar, Saim (2021-08-01)
In this work, platinum(0) nanoparticles are deposited on the surface of magnetic cobalt ferrite forming magnetically separable Pt-0/CoFe2O4 nanoparticles, which are efficient catalysts in H-2 generation from the hydrolysis...
Highly conjugated visible and near-infrared light photoinitiating systems for radical and cationic polymerizations
Suerkan, Ali; Aydan Alkan, Ecem; Kaya, Kerem; Udum, Yasemin; Toppare, Levent Kamil; Yağcı, Yusuf (2021-05-01)
In this communication, we report highly conjugated thiophenes having [1,2,5]-thiadiazolo and [1,2,5]-selenadiazolo [3,4-f]-benzo [1,2,3] triazole in conjunction with diphenyliodonium hexafluorophosphate salt(DPI) as new vi...
Polyhedral oligomeric silsesquioxanes appended conjugated soluble polymers based on thieno[3,4-c]pyrrole-4,6,dione acceptor unit
Çakal, Deniz; CİHANER, ATİLLA; Önal, Ahmet Muhtar (2021-05-01)
A series of new donor-acceptor-donor type fluorescent molecules incorporating thieno[3,4-c]pyrrole-4,6-dione (TPD) as the acceptor unit were synthesized. TPD acceptor unit was modified with polyhedral oligomeric silsesquio...
Highly-sensitive and fast detection of human telomeric G-Quadruplex DNA based on a hemin-conjugated fluorescent metal-organic framework platform
Javan Kouzegaran, Vahid; Farhadi, Khalil; Forough, Mehrdad; Bahram, Morteza; Persil Çetinkol, Özgül (Elsevier BV, 2021-04-15)
© 2021 Elsevier B.V.The formation of G-quadruplex (G4) structures in Human telomeric DNA (H-Telo) has been demonstrated to inhibit the activity of telomerase enzyme that is associated with the proliferation of many cancer ...
PbSe Nanorod Degree of Organization Dictated by the Ligand Structure
Asil Alptekin, Demet; Hacıefendioğlu, Tuğba (2021-04-14)
ENHANCED PHOTOCURRENT IN MIXED HALIDE TREAT ED QUANTUM DOT SOLAR CELLS
Hacıefendioğlu, Tuğba; Asil Alptekin, Demet (2021-04-12)
Polymer interfaces with carbon nanostructures: First principles density functional theory and molecular dynamics study of polyetheretherketone adsorption on graphene and nanotubes
Toraman, Gozdenur; Sert, Elif; Gulasik, Hasan; Toffolı, Danıele; Toffoli, Hande; Gürses, Ercan (2021-04-01)
The interface of polyetheretherketone (PEEK) with carbon nanotubes (CNTs) and graphene is investigated using density functional theory and molecular dynamics within the REAXFF-lg interatomic interaction framework. The depe...
A robust optimization approach for the breast cancer targeted design of PEtOx-b-PLA polymersomes
Oz, Umut Can; Bolat, Zeynep Busra; Ozkose, Umut Ugur; Gulyuz, Sevgi; Kucukturkmen, Berrin; Khalily, Melek Parlak; Özçubukçu, Salih; Yilmaz, Ozgur; Telci, Dilek; ESENDAĞLI, GÜNEŞ; Sahin, Fikrettin; Bozkir, Asuman (2021-04-01)
© 2021 Elsevier B.V.The equipping of nanoparticles with the peptide moiety recognizing a particular receptor, enables cell or tissue-specific targeting, therefore the optimization of the targeted nanoparticles is a key fac...
Synthesis and evaluation of tumor-homing peptides for targeting prostate cancer
Nezir, Ayca Ece; PARLAK KHALİLY, MELEK; Gulyuz, Sevgi; Özçubukçu, Salih; KÜÇÜKGÜZEL, ŞÜKRİYE GÜNİZ; Yilmaz, Ozgur; TELCİ, DİLEK (2021-04-01)
High toxicity caused by chemotherapeutic drugs and the acquisition of drug resistance by cancer cells are the major drawbacks in cancer therapy. A promising approach to overcome the posed barriers is conjugating tumor-homi...
Crystal structure determination and computational studies of 1,4-dihydropyridine derivatives as selective T-type calcium channel blockers
GÜNDÜZ, MİYASE GÖZDE; Armakovic, Sanja J.; Dengiz, Çağatay; Tahir, Muhammad Nawaz; Armakovic, Stevan (2021-04-01)
Different types of calcium channels are crucial regulators of many key physiological functions throughout the body. Therefore, calcium channel modulators are accepted as precious molecules for the therapeutic intervention ...
Altering Electronic and Optical Properties of Novel Benzothiadiazole Comprising Homopolymers via π Bridges
Zeytun Karaman, Cansu; Göker, Seza; Özdemir Hacıoğlu, Şerife; Hacıefendioğlu, Tuğba; Yıldırım, Erol; Toppare, Levent Kamil (2021-03-01)
Four novel benzo[c][1,2,5]thiadiazole comprising monomers namely 5-fluoro-6-((2-octyldodecyl)oxy)-4,7-di(thiophen-2-yl)benzo[c][1,2,5]thiadiazole (TBTT), 5-fluoro-4,7-bis(4-hexylthiophen-2-yl)-6-((2-octyldodecyl)oxy)benzo[...
Altering Electronic and Optical Properties of Novel Benzothiadiazole Comprising Homopolymers via pi Bridges
Zeytun Karaman, Cansu; Goeker, Seza; Hacioglu, Serife O.; Haciefendioglu, Tugba; Yıldırım, Erol; Toppare, Levent Kamil (2021-03-01)
Four novel benzo[c][1,2,5]thiadiazole comprising monomers namely 5-fluoro-6-((2-octyldodecyl)oxy)-4,7-di(thiophen-2-yl)benzo[c][1,2,5]thiadiazole (TBTT), 5-fluoro-4,7-bis(4-hexylthiophen-2-yl)-6-((2-octyldodecyl)oxy)benzo[...
Ultimate COVID-19 Detection Protocol Based on Saliva Sampling and qRT-PCR with Risk Probability Assessment.
Won, Joungha; Kazan, Hasan Hüseyin; Kwon, Jea; Park, Myungsun; Ergun, Mehmet Ali; Özcan Kabasakal, Süreyya; Choi, Byung Yoon; Heo, Won Do; Lee, C Justin (2021-02-28)
In the era of COVID-19 outbreak, various efforts are undertaken to develop a quick, easy, inexpensive, and accurate way for diagnosis. Although many commercial diagnostic kits are available, detailed scientific evaluation ...
The synthesis of chiral β-naphthyl-β-sulfanyl ketones via enantioselective sulfa-Michael reaction in the presence of a bifunctional cinchona/sulfonamide organocatalyst
Tözendemir, Deniz; Tanyeli, Cihangir (2021-02-01)
Cinchona alkaloid-derived organocatalysts are widely employed in various asymmetric transformations, yielding products with high enantiopurity. In this respect, a bifunctional quinine-derived sulfonamide organocatalyst was...
Assessment of solid phase microextraction as a sample preparation tool for untargeted analysis of brain tissue using liquid chromatography-mass spectrometry
Reyes-Garces, Nathaly; Boyacı, Ezel; Gomez-Rios, German A.; Olkowicz, Mariola; Monnin, Cian; Bojko, Barbara; Vuckovic, Dajana; Pawliszyn, Janusz (2021-02-01)
This work presents an evaluation of solid-phase microextraction (SPME) SPME in combination with liquid chromatography-high resolution mass spectrometry (LC-HRMS) as an analytical approach for untargeted brain analysis. The...
Investigation of the biological and photophysicochemical properties of new non-peripheral fluorinated phthalocyanines
Çelik, Çetin; Farajzadeh, Nazli; Akin, Mustafa; YAŞA ATMACA, Göknur; Sağlam, Özgül; ŞAKİ, NESLİHAN; ERDOĞMUŞ, Ali; Koçak, Makbule (2021-02-01)
This study presents the synthesis of a series of new tetra-substituted phthalocyanines bearing 3,5-bis(trifluoromethyl)phenoxy groups at non-peripheral positions. The resulting macromolecules were characterized by performi...
Iron-Catalyzed α-C-H Cyanation of Simple and Complex Tertiary Amines.
Yilmaz, Ozgur; Dengiz, Çağatay; Emmert, Marion H (American Chemical Society (ACS), 2021-01-19)
This manuscript details the development of a general and mild protocol for the α-C–H cyanation of tertiary amines and its application in late-stage functionalization. Suitable substrates include tertiary aliphatic, benzyli...
Indenoquinoxalinone based conjugated polymer substrate for laccase biosensor
Cevher, Şevki Can; Çırpan, Ali; Bekmezci, Sıddıka Aybüke; Soylemez, Saniye; Udum, Yasemin Arslan; Toppare, Levent Kamil (Elsevier BV, 2021-01-01)
This paper describes the synthesis and characterization of a novel monomer (6,9-bis(4-hexylthiophen-2-yl)-11H-indeno[2,1-b]quinoxalin-11-one (M1)). M1 monomer was electrochemically polymerized on the electrode surface and ...
A machine learning algorithm to differentiate bipolar disorder from major depressive disorder using an online mental health questionnaire and blood biomarker data
Tomasik, Jakub; Han, Sung Yeon Sarah; Barton-Owen, Giles; Mirea, Dan-Mircea; Martin-Key, Nayra A.; Rustogi, Nitin; Lago, Santiago G.; Olmert, Tony; Cooper, Jason D.; Özcan Kabasakal, Süreyya; Eljasz, Pawel; Thomas, Gregoire; Tuytten, Robin; Metcalfe, Tim; Schei, Thea S.; Farrag, Lynn P.; Friend, Lauren V.; Bell, Emily; Cowell, Dan; Bahn, Sabine (2021-01-01)
The vast personal and economic burden of mood disorders is largely caused by their under- and misdiagnosis, which is associated with ineffective treatment and worsening of outcomes. Here, we aimed to develop a diagnostic a...
Untargeted metabolomics profiling of skeletal muscle samples from malignant hyperthermia susceptible patients
Bojko, Barbara; Vasiljevic, Tijana; Boyacı, Ezel; Roszkowska, Anna; Kraeva, Natalia; Moreno, Carlos A. Ibarra; Koivu, Annabel; Wasowicz, Marcin; Hanna, Amy; Hamilton, Susan; Riazi, Sheila; Pawliszyn, Janusz (Springer Science and Business Media LLC, 2021-01-01)
Purpose Malignant hyperthermia (MH) is a potentially fatal hypermetabolic condition triggered by certain anesthetics and caused by defective calcium homeostasis in skeletal muscle cells. Recent evidence has revealed impair...
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