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Investigating the behavior of D-glucose, D-fructose, and D-allulose in aqueous media by molecular dynamics simulations
Buğday, Zinnur Yağmur; Bayramoğlu, Beste; Öztop, Halil Mecit (2025-07-01)
Isomeric monosaccharides may have different hydration behaviors, leading to distinct physicochemical properties in solutions. In this work, the aqueous behavior, structure, and hydration properties of D-allulose, D-glucose...
Psyllium and monogylceride addition in breadmaking: Molecular interactions, nano- and micro-structural characterization, physical properties, sensory properties, and starch digestibility
Güven, Özge; Şensoy, İlkay; De Leyn, Ingrid; Dewettinck, Koen; Van Bockstaele, Filip (2025-06-01)
Psyllium, a soluble dietary fiber, was combined with a commercial monoglyceride in the formulation of bread, replacing wheat flour with psyllium at ratios of 0:100, 2:98 and 5:95 (g psyllium: g flour weight), with the brea...
A comprehensive mathematical modeling study for temperature evolution during radio frequency assisted honey decrystallization
Karatas, Ozan; Uyar, Rahmi; Son, Ezgi; Coşkun, Eda; Mert, Behiç; Marra, Francesco; ERDOĞDU, FERRUH (2025-03-01)
In industrial settings, honey decrystallization is conducted by conventional thermal processing with hot water (12–18 h) or air (24–36 h) at around 60 °C. Considering the demands for a green and sustainable efficient proce...
Characterization of Plant-Based Raw Materials Used in Meat Analog Manufacture
Bulgaru, Viorica; Mazur, Mihail; Netreba, Natalia; Paiu, Sergiu; Dragancea, Veronica; Gurev, Angela; Sturza, Rodica; Şensoy, İlkay; Ghendov-Mosanu, Aliona (2025-02-01)
The purpose of this research was to investigate the characteristics of different plant-based sources rich in protein, chickpea flour (CPF), hazelnut oil cake (HOC), soy protein isolate (SPI) and concentrate (SPC), and pea ...
Core-shell aerogel design for enhanced oral insulin delivery
Ozesme Taylan, Gozde; Illanes-Bordomás, Carlos; Güven, Özge; Erkan, Ece; Erünsal, Sevil Çıkrıkcı; Öztop, Halil Mecit; García-González, Carlos A. (2025-01-25)
Current protein-based therapies often rely on intravenous and subcutaneous injections leading to patient discomfort due to the need for frequent administration. Oral administration route presents a more patient-friendly al...
Effect of Extraction Methods and Preheat Treatments on the Functional Properties of Pumpkin Seed Protein Concentrate
Taş, Ozan; Şümnü, Servet Gülüm; Oztop, Mecit Halil (2024-12-25)
This study explores the effect of different extraction methods and preheat treatments in obtaining protein concentrate from pumpkin seed flour. The effects on the yield and functional properties of pumpkin seed protein con...
The use of chitosan aerogels as an adsorbent for the regeneration of frying oil
Delice, Feyza Nur; Namlı, Serap; Uzun, Merve Akpınar; GÜVEN, ÖZGE; TEKİN, AZİZ; Öztop, Halil Mecit (2024-11-01)
One of the most commonly used food preparation methods is deep-fat frying. The improvement of the quality of used frying oil (UFO) is important because the reuse of frying oil could provide significant savings to the food ...
Optimization of phenolic extracts of sugar beet leaves with minimal chlorophyll content using response surface methodology (RSM) to enhance the oxidative stability of different oils
Ebrahimi, Peyman; Bayram, İpek; Mihaylova, Dasha; Decker, Eric A.; Lante, Anna (2024-09-08)
A strategy to minimize the chlorophyll content in the phenolic extract of sugar beet leaves: Can this extract work as a natural antioxidant in vegetable oils?
Ebrahimi, Peyman; Bayram, İpek; Mihaylova, Dasha; Lante, Anna (2024-09-01)
The presence of chlorophylls in phenolic extracts may limit their use in food products due to undesirable coloration. This project seeks to minimize the co-extraction of chlorophylls during the ultrasonic-assisted extracti...
A machine learning-guided modeling approach to the kinetics of α-tocopherol and myricetin synergism in bulk oil oxidation
Parra-Escudero, Carlos; Bayram, İpek; Decker, Eric A.; Singh, Shyamyanshikumar; Corvalan, Carlos; Lu, Jiakai (2024-09-01)
The shelf-life and quality of food products depend heavily on antioxidants, which protect lipids from free radical degradation. α-Tocopherol and myricetin, two potent antioxidants, synergistically enhance the prevention of...
Synergistic quantification of mixed insulin preparations using time domain NMR techniques
Alam, Hani; Ozesme Taylan, Gozde; Yamalı, Cem; Öztop, Halil Mecit (2024-09-01)
Diabetes patients often rely on tailored insulin therapies, necessitating precise blends of various insulin types to achieve optimal pharmacokinetic profiles, including the quantity and action duration of insulin absorptio...
Unravelling temperature-dependent molecular changes in hydrated wheat and maize starches using 1H time-domain NMR
van Rooyen, Jana; Grunin, Leonid; Öztop, Halil Mecit; Kruk, Danuta; Manley, Marena (2024-08-01)
This study proved that time-domain NMR (TD-NMR) experiments can accurately demonstrate the interaction between starch (wheat and maize) and water and the distribution of water molecules in starch-water systems during heati...
Early shelf-life prediction of soybean oil using computational modeling of tocopherol depletion kinetics during lipid oxidation
Bayram, İpek; Parra-Escudero, Carlos; Decker, Eric A.; Lu, Jiakai (2024-04-28)
Textural, rheological, melting properties, particle size distribution, and NMR relaxometry of cocoa hazelnut spread with inulin-stevia addition as sugar replacer
Berk, Berkay; Cosar, Sumeyye; Mazı, Bekir G.; Öztop, Halil Mecit (2024-04-01)
This study investigated the influence of substituting 60, 80, and 100% of the sugar in traditional cocoa hazelnut paste (control) formulation with inulin-stevia (90:10, w/w) mixture on textural and rheological characterist...
Crystallization of sucrose by using microwave vacuum evaporation
Ibis, Ozge Ilgin; Bugday, Yagmur Balabanli; Aljurf, Bodoor Nabil; Goksu, Aylin Ozgur; Solmaz, Hatice; Öztop, Halil Mecit; Şümnü, Servet Gülüm (2024-03-01)
Sucrose crystallization was performed by using a custom designed microwave vacuum evaporation system. Process was designed to mimic a semi-batch crystallization starting from beet syrup concentration to crystal slurry form...
Effects of alkaline pH and gallic acid enrichment on the physicochemical properties of sesame protein and common vetch starch-based composite films
Ertan, Kübra; Şahin, Serpil; Şümnü, Servet Gülüm (2024-02-01)
In this study, sesame (Sesamum indicum L.) meal protein and common vetch (Vicia sativa L.) starch were extracted and used to obtain biodegradable composite films at different pH values (7, 9, and 11). Films were plasticize...
Functional Nanofibers for Active Packaging: Elenolic Acid-Loaded Chitosan/PEO Blends
Aydoğdu Emir, Ayça; Gürsel, Dilara; Yörüksoy, İlayda; Yıldız, Eda (2024-01-01)
The aim of this study is to create electrospun nanofibers based on chitosan/PEO (polyethylene oxide) and elenolic acid and to characterize them as active film materials. Elenolic acid was incorporated into the chitosan/PEO...
Exploring Noncentrifugal Sugar as a Partial Replacement for White Sugar in Low Methoxyl Pectin Confectionery Gels: Impacts on Physical and Rheological Properties
Fakhar, Hafiz Imran; Cavdaroglu, Elif; Hayat, Muhammad Qasim; Janjua, Hussnain A.; Öztop, Halil Mecit (2024-01-01)
Noncentrifugal sugar (NCS) is an unrefined, dark brown sugar containing minerals and plant secondary metabolites, unlike refined white sugar (WS). This study explored using NCS in confectionary jellies as an alternative su...
Phage Therapy Against Pathogenic Escherichia coli (O104:H4, O157:H7, and O26) Strains in Irrigation Water During Garden Cress (Lepidium sativum Linn.) Vegetation
Iskender, Irem; Soyer, Yeşim (2023-12-01)
Fresh produce outbreaks have increased worldwide. Foodborne pathogens are transmitted mostly by contaminated water, and elimination is harder after the transmission. To eliminate pathogens in fresh produce, chemical preven...
Extraction of Pumpkin Seed Protein by Using Different Methods
Taş, Ozan; Öztop, Halil Mecit (2023-11-27)
Extraction of Pumpkin Seed Protein by Using Different Methods Mr Ozan Tas1 , Professor Mecit Halil Oztop1 1Middle East Technical University Aim: Pumpkin seed is one of the most important agro-industrial wastes and is g...
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