Graduate School of Informatics

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Recent Submissions

Data-driven alarm parameter optimization Eylen, Tayfun; Eren, Pekin Erhan; Koçyiğit, Altan (2025-05-01) Most manufacturing sector businesses utilize advanced control mechanisms to sustain their ongoing operations. An alarm management system is one of these control mechanisms that works as a safety barrier, and it contains al...
Class distance weighted cross entropy loss for classification of disease severity Polat, Gorkem; Çağlar, Ümit Mert; Temizel, Alptekin (2025-04-01) Assessing disease severity with ordinal classes, where each class reflects increasing severity levels, benefits from loss functions designed for this ordinal structure. Traditional categorical loss functions, like Cross-En...
Sustainable biodiesel production from oil crops: The impact of bio-nutrient recycling on yield and farmer technology acceptance Özdemir, Serkan; Ozer, Hasan; Ozdemir, Saim; Dede, Omer Hulusi (2025-03-01) Circular utilization of biowaste through biofuel production is a key priority for many waste-producing facilities seeking to internally supply biofuels and to reduce greenhouse gases. This study assesses the role of biowas...
EnSCAN: ENSEMBLE SCORING FOR PRIORITIZING CAUSATIVE VARIANTS ACROSS MULTI-PLATFORM GWAS FOR LATE-ONSET ALZHEIMER'S DISEASE Erdoğan, Onur; Aydın Son, Yeşim; İyigün, Cem; Department of Medical Informatics (2025-2-21) Late-onset Alzheimer's Disease (LOAD) represents a progressive and complex neurodegenerative condition prevalent among the elderly demographic. Manifesting through cognitive deterioration, including memory impairment and d...
Presenting predictions and performance of probabilistic models for clinical decision support in trauma care Alptekin, Cansu; Wohlgemut, Jared M.; Perkins, Zane B.; Marsh, William; Tai, Nigel R. M.; Yet, Barbaros (2025-02-01) Introduction: Both predictions and performance of clinical predictive models can be presented with various verbal and visual representations. This study aims to investigate how different risk and performance presentations ...
A Review of LLM Security: Threats and Mitigations Günay, Bengi; Tezcan, Cihangir; Department of Cybersecurity (2025-1-23) Large Language Models (LLMs) are advanced AI systems trained on massive datasets to process and generate natural language. These models can understand, summarize, and create human-like text with remarkable accuracy. Sinc...
JAMMER DETECTION IN AUTONOMOUS VEHICLES WITH MACHINE LEARNING Demiryürek, Mert; Taşkaya Temizel, Tuğba; Department of Information Systems (2025-1-23) Wireless communication systems of autonomous vehicles may be vulnerable to threats such as jammer attacks. As a result of these attacks, operational failures and security problems may occur. This study aims to classify whi...
AI in the classroom: Exploring students' interaction with ChatGPT in programming learning Guner, Hacer; Er, Erkan (2025-01-15) As being more prevalent in educational settings, understanding the impact of artificial intelligence tools on student behaviors and interactions has become crucial. In this regard, this study investigates the dynamic inter...
A Survey on Password-free Authentication Method: Passkey Doğan, Sait Göktuğ; Tezcan, Cihangir; Department of Cybersecurity (2025-1-15) When a need for to authenticate someone or something, the first answer that comes to mind is to use passwords. While implemented and used properly, passwords are more than enough to securely authenticate. But like everythi...
ASSESSING ADVANCED RETRIEVALAUGMENTED GENERATION TECHNIQUES FOR QUESTION ANSWERING: A CASE STUDY ON GOVERNMENTAL SERVICES Alzariqi, Abdullah Talat Ahmed Mohammed; Taşkaya Temizel, Tuğba; Department of Information Systems (2025-1-15) This case study evaluates advanced Retrieval-Augmented Generation (RAG) methods to enhance question answering in conversational AI for government services, focusing on data from the Ministry of Health and Prevention. It as...
Comprehensive whole-genome sequencing reveals origins of mutational signatures associated with aging, mismatch repair deficiency and temozolomide chemotherapy Hwang, Taejoo; Sitko, Lukasz Karol; Khoirunnisa, Ratih; Navarro-Aguad, Fernanda; Samuel, David M.; Park, Hajoong; Cheon, Banyoon; Mutsnaini, Luthfiyyah; Lee, Jaewoong; Otlu Sarıtaş, Burçak; Takeda, Shunichi; Lee, Semin; Ivanov, Dmitri; Gartner, Anton (2025-01-13) In a comprehensive study to decipher the multi-layered response to the chemotherapeutic agent temozolomide (TMZ), we analyzed 427 genomes and determined mutational patterns in a collection of ∼40 isogenic DNA repair-defici...
API Security Guideline for Developers and Product Owners Akgündüz, Okan; Tezcan, Cihangir; Department of Cognitive Sciences (2025-1-10) A security guideline with security topics, practices, and recommendations to consider when designing, developing, and maintaining an API service for developers and product owners.
Security Assessment of the Smartcard Systems at Middle East Technical University akçören, berkay; Tezcan, Cihangir; Department of Cybersecurity (2025-1-10) Smartcards are portable devices that can communicate wirelessly and contain microchips capable of transferring, processing or storing data. They serve practical and reliable solutions for everyday problems such as identifi...
INVESTIGATING THE SEMANTIC SIMILARITY EFFECT ON DELAYED FREE RECALL USING WORD EMBEDDINGS Büyükyaprak, Burak; Yet, Barbaros; Kılıç Özhan, Aslı; Department of Cognitive Sciences (2025-1-10) Episodic memory is a type of long-term memory that encodes and retrieves personal experiences associated with their context. Previous episodic memory studies showed that the context or pre-existing knowledge about retrieve...
Brain Network Connectivity of the N-Back Task in Schizophrenia Groups According to M1 Receptor Polymorphism Çağlayan, Ece; Çakır, Murat Perit; Kır, Yağmur; Department of Medical Informatics (2025-1-10) This study explores the impact of clozapine, an atypical antipsychotic, on cognitive function and brain connectivity in 43 schizophrenia patients, focusing on the M1 muscarinic receptor and its rs2067477 polymorphism. Buil...
FACILITATING COLLABORATIVE DEEPFAKE DETECTION BASED ON BLOCKCHAIN TECHNOLOGY AND REPUTATION Zemin, Mustafa; Baykal, Nazife; Department of Information Systems (2025-1-07) The increasing popularity of deepfake technology is progressively posing a significant threat to information integrity and security. There are numerous solutions to detect deepfakes, but they usually fail to detect all o...
A robust approach for predicting mutation effects on transcription factor binding: insights from mutational signatures in 560 breast cancer samples Kılınç, Hüseyin Hilmi; Otlu Sarıtaş, Burçak; Department of Bioinformatics (2025-1-07) Somatic mutations, particularly in non-coding regions, can perturb transcription factor (TF)-DNA interactions, influencing gene regulatory networks and contributing to cancer development. Thus, they require further compreh...
DEFINING CULTURE AND PEOPLE RELATED PROCESSES IN ADVANCED DATA ANALYTICS PROJECTS AFSHAR GHOCHANI, TINA; Özcan Top, Özden; Aysolmaz, Banu; Department of Information Systems (2025-1) Advanced data analytics (ADA), as an emerging field, empowers companies in gaining competitive advantages by offering insights derived from data. To derive business value from ADA, organizations must develop various capa...
Impact of Land Use Change on Lake Pollution Dynamics: A Case Study of Sapanca Lake, Turkey Özdemir, Serkan; Celebi, Ahmet; Dede, Gulgun; Maghrebi, Mohsen; Danandeh Mehr, Ali (2025-01-01) Modeling non-point source pollution dynamics in inland lake basins is essential for safeguarding water quality, maintaining ecosystem integrity, protecting public health, and advancing long-term environmental sustainabilit...
Assessing student perceptions and use of instructor versus AI-generated feedback Er, Erkan; AKÇAPINAR, GÖKHAN; BAYAZIT, ALPER; Noroozi, Omid; Banihashem, Seyyed Kazem (2024-12-27) Despite the growing research interest in the use of large language models for feedback provision, it still remains unknown how students perceive and use AI-generated feedback compared to instructor feedback in authentic se...

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