Graduate School of Natural and Applied Sciences

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Recent Submissions

A predictive metabolomic model for FLT3 and NPM1 mutations in Acute Myeloid Leukemia patients Gerekci̇ Yeşi̇lyurt, Selin; Koyun, Derya; TOPRAK, SELAMİ KOÇAK; ÖZCAN, MUHİT; Özen, Can (2025-08-01) Cytogenetic abnormalities and gene mutations are essential for planning AML treatment. However, in Turkey, test results typically take 14–30 days. This delay emphasizes a critical need for rapid methods to deliver clinical...
Assessment of the Effect of Uncertainties Associated with Input Parameters on Failure of Earth-fill Dams Diler Övenler, Dilan; Yanmaz, A. Melih; Zaifoğlu , Hasan; Department of Civil Engineering (2025-6-23) Dam failures have major effects on the environment and human life, and lead to serious financial losses. Flash floods have become increasingly frequent in recent years and are considered a significant factor contributing t...
Development of flowpath design tool for gas turbine engines Kündeş, Necmettin Anıl; Baran, Özgür Uğraş; Aksel, Mehmet Haluk; Department of Mechanical Engineering (2025-6-20) The conceptual design phase of a gas turbine engine involves a significant number of iterations between thermodynamic cycle analysis and turbomachinery aerodynamic designs to satisfy all performance requirements. These ite...
THE EFFECT OF TEMPERING ON MICROSTRUCTURE AND HARDNESS OF Fe-1C-2Si (wt%) AND Fe-1C-2Si-2Cu-1Ni (wt%) NANOBAINITIC STEELS Öztürk Taş, Zeynep; Ögel, Bilgehan; Kalkanlı, Ali; Department of Metallurgical and Materials Engineering (2025-6-20) Nanostructured bainitic steels have been a focus of interest in recent years, since they exhibit extremely high strength without compromising from toughness. With careful alloy design, excellent combinations of tensile str...
Estimation of hydraulic conductivity fields through generative adversarial networks and Bayesian inference Çelebi, Emrehan Berkay; Aksoy, Ayşegül; Kitanidis, Peter; Department of Environmental Engineering (2025-6-20) Accurate characterization of the subsurface is critical for many engineering applications, ranging from groundwater supply to carbon sequestration. Mostly, inverse modeling is ill-posed due to numerous parameters to estima...
In-depth structural characterization of perovskite and kesterite solar cells with photoelectron spectroscopy Javed, Ahmed; Selçuk , Yerci; Mustafa , Yaşa; Department of Micro and Nanotechnology (2025-6-19) The new developments in the photovoltaic industry have introduced alternative materials that have the potential to replace the expensive silicon technology and play a pivotal role in resolving the global energy issues. The...
Modeling and design optimization of a two stage oleo-pneumatic landing gear Canıtez, Barış; Çalışkan, Hakan; Department of Mechanical Engineering (2025-6-16) This thesis presents a comprehensive investigation into the dynamic response optimization of a helicopter landing gear system equipped with a two-stage, valve-metered oleo-pneumatic shock absorber. The landing gear model i...
Synthesis and Characterization of Graphene Oxide/Metal Oxide Nanostructures and Study of Their Catalytic Activities for Water Splitting Gedik, Başak; Nalbant, Emren; Department of Chemistry (2025-6-16) With the rising demand for energy and the depletion of fossil fuel reserves, the need for cleaner and more sustainable energy sources has become urgent. Hydrogen stands out as a promising energy carrier due to its high eff...
Investigation of primary school teachers' cyber resilience levels Koca, Boran; Delialioğlu, Ömer; İstanbullu, Aslıhan; Computational Design and Fabrication Technologies in Department of Architecture (2025-6-13) This study aims to examine the cyber resilience levels of primary school teachers within the context of the National Institute of Standards and Technology (NIST) Cybersecurity Framework (CSF) and their relationship with de...
SYNTHESIS OF THIOPHENE π-BRIDGE MODIFIED BENZODITHIOPHENE AND QUINOXALINE BASED CONJUGATED POLYMERS FOR ORGANIC BULK HETEROJUNCTION SOLAR CELL APPLICATIONS Türkatar, Meltem; Çırpan, Ali; Hızalan Özsoy, Gönül; Department of Polymer Science and Technology (2025-6-13) In this study, six different donor-acceptor type benzodithiophene–quinoxaline-based conjugated polymers were synthesized via Stille cross-coupling reaction, incorporating a thiophene π-bridge, to investigate the effect of ...
COMPARING GREEN BUILDING CERTIFICATION SYSTEMS FOR EVALUATING ADAPTIVE REUSE OF HERITAGE BUILDINGS: THE CASE OF BOĞAZİÇİ UNIVERSITY GÖZLÜKULE RESEARCH CENTER Kol, Şimal; Elias Özkan, Soofia Tahira; Department of Building Science in Architecture (2025-6-12) This study explores the potential for heritage buildings to achieve green building certification through adaptive reuse. The research focuses on four leading certification systems: LEED (United States), BREEAM (United King...
DRBEM SOLUTIONS OF REGULARLY AND SINGULARLY PERTURBED MAGNETOHYDRODYNAMIC DUCT FLOW PROBLEMS Arslan Ölçer, Sinem; Tezer, Münevver; Department of Mathematics (2025-6-10) This thesis investigates the dual reciprocity boundary element method (DRBEM) solutions of magnetohydrodynamic (MHD) flow problems in rectangular ducts, which are either regularly or singularly perturbed, under the influen...
Agrivoltaic system design for sugar beets and wheat in central Anatolia Yalçın, Ömer; Kuzyaka, Duygu; ÖZDEN, TALAT (2025-06-01) Agrivoltaic systems, which integrate photovoltaic (PV) panels with the usage of agricultural land, emerge as a promising strategy by facilitating the simultaneous generation of renewable energy alongside the cultivation of...
Detecting transfer trip patterns in public transport using smart card data Özer, Fehmi Can; Tüydeş Yaman, Hediye; Department of Geodetic and Geographical Information Technologies (2025-6) Public transport (PT) decisions are affected significantly by the potential of and need for trip chaining, which allows transfers across different modes. Thus, detection and analysis of such transfers at PT stops can suppo...
A HIGH-FIDELITY NON-INTRUSIVE REDUCED-ORDER MODEL FOR THE STATIC AEROELASTIC BEHAVIOR OF LIFTING SURFACES Özkaya, Zarif Özge; Kayran, Altan; Department of Aerospace Engineering (2025-6) This study proposes an efficient, low-cost reduced-order method for analyzing the static aeroelastic behavior of a three-dimensional sweptback wing, focusing on the impact of wing elasticity on model efficiency. The prim...
Microbial dysbiosis fuels STING-driven autoinflammation through cyclic dinucleotides Shibahara, Takayuki; et. al. (2025-06-01) Aberrant activation of the stimulator of interferon genes (STING) pathway is a hallmark of autoinflammatory disorders such as STING-associated vasculopathy with onset in infancy (SAVI), characterized by systemic inflammati...
Taxonomic and functional diversity of bird communities of the Anatolian diagonal Gürol, Ilgın Ertan; Ambarlı, Didem; Department of Biology (2025-5-28) Birds, integral to ecosystem functioning, are subjected to biodiversity crisis driven by anthropogenic stressors, including land cover conversion, pollution, and climate change. The Anatolian Diagonal running across Türkiy...
Development of a MEMS-based microfluidic electrochemical biosensor for the detection of circulating tumor DNA Çağlayan Arslan, Zeynep; Külah, Haluk; Department of Electrical and Electronics Engineering (2025-5-26) Recent advances in microfluidic biosensors have significantly enhanced the analytical performance of diagnostic platforms, particularly for cancer biomarker detection. Among these, electrochemical biosensors are widely pre...
Exploring middle school students’ design thinking processes: An extra-curricular program development Aytekin Bircan, Merve; Yıldırım, İbrahim Soner; Öztürk, Elif; Department of Computer Education and Instructional Technology (2025-5-20) The present study aimed to examine the design thinking processes of 6th grade students in society and science centers by developing an extra-curricular program based on design thinking approach. It was attempted to explore...
INVESTIGATION OF STRATEGIES AND MATHEMATICAL CREATIVITY OF 8TH GRADE GIFTED STUDENTS ON NONLINEAR REALISTIC GENERALIZATION TASKS Tuncer, Zeynep; Işıksal Bostan, Mine; Department of Mathematics Education (2025-5-16) The present study aims to investigate the strategies that 8th-grade gifted students use while solving alternative types of nonlinear realistic generalization tasks and their mathematical creativity while solving these ta...

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