Biomaterials and Tissue Engineering Application and Research Center (BİOMATEN), Article

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KÖSE, GAMZE (6)
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2010 - 2019 (20)

Recent Submissions

The effect of high-temperature on foamed concrete
CANBAZ, MEHMET; Dakman, Hafid; Arslan, Baris; Büyüksungur, Arda (2019-07-01)
Within the scope of this study, the foam solution was prepared by properly mixing sulfonate based foam agent with water. Furthermore, this solution was mixed with the mixture of fine sand, cement, and water to produce foam...
Surface modification of Ti6Al4V by micro-arc oxidation in AgC2H3O2-containing electrolyte
Aydogan, Dilek Teker; Muhaffel, Faiz; Acar, Ozge Karabiyik; Topcuoglu, Emine Nursen; Kulekci, Hatice Guven; Kose, Gamze Torun; Baydoğan, Murat; Çimenoğlu, Hüseyin (2018-09-01)
This study focuses on the biological properties of Ti6Al4V after employing micro-arc oxidation in sodium phosphateand calcium acetate-containing electrolyte with and without addition of silver acetate. After micro-arc oxid...
Evaluation of Threshold Values for Root Canal Filling Voids in Micro-CT and Nano-CT Images
Orhan, Kaan; Jacobs, Reinhilde; Celikten, Berkan; Huang, Yan; de Faria Vasconcelos, Karla; Nicolielo, Laura Ferreira Pinheiro; Buyuksungur, Arda; Van Dessel, Jeroen (Hindawi Limited, 2018-7-16)
While several materials and techniques have been used to assess the quality of root canal fillings in micro-CT images, the lack of standardization in scanning protocols has produced conflicting results. Hence, the aim of t...
Chondrogenic potential of macroporous biodegradable cryogels based on synthetic poly(alpha-amino acids)
Sedlacik, T.; Acar, O. K.; Studenovska, H.; Kotelnikov, I.; Kucka, J.; Konecna, Z.; Zikmund, T.; Kaiser, J.; KÖSE, GAMZE; Rypacek, F. (Royal Society of Chemistry (RSC), 2018-01-14)
In this study, the potential of highly porous hydrogels based on biodegradable synthetic poly(alpha-amino acids) to support proliferation and chondrogenesis of human dental pulp stem cells (hDPSCs) was investigated. Covale...
Magnesium doping on TiN coatings affects mesenchymal stem cell differentiation and proliferation positively in a dose-dependent manner
ÖNDER, Sakip; Calikoglu-Koyuncu, Ayse Ceren; Kazmanli, Kursat; Urgen, Mustafa; Kök, Fatma Neşe; KÖSE, GAMZE (IOS Press, 2018-01-01)
BACKGROUND: In vitro evaluation of cell-surface interactions for hard tissue implants have mostly been done using osteoblasts. However, when an implant is placed in the body, mesenchymal stem cells (MSCs) play a major role...
Optimisation of micro-arc oxidation electrolyte for fabrication of antibacterial coating on titanium
Aydogan, Dilek Teker; Muhaffel, Faiz; Kilic, Meryem Menekse; Acar, Ozge Karabiyik; Cempura, Grzegorz; Baydoğan, Murat; Gül-karagüler, Nevin; Kose, Gamze Torun; Czyrska-Filemonowicz, Aleksandra; Çimenoğlu, Hüseyin (2018-01-01)
This study has been carried out to optimise the silver (Ag) content of the coating synthesised on commercially pure titanium (Cp-Ti, Grade 4) for biomedical applications by micro-arc oxidation (MAO) process. The MAO proces...
Gene Therapy Strategies in Bone Tissue Engineering and Current Clinical Applications
Atasoy-Zeybek, Aysegul; KÖSE, GAMZE (2018-01-01)
Gene therapy provides a promising approach for regeneration and repair of injured bone. Application of gene therapy has displayed increased efficiency in various animal models and preclinical trials in comparison with trad...
Influence of STRO-1 selection on osteogenic potential of human tooth germ derived mesenchymal stem cells
Ercal, Pinar; Pekozer, Gorke G.; Gumru, Osman Z.; KÖSE, GAMZE; Ramazanoglu, Mustafa (Elsevier BV, 2017-10-01)
Mesenchymal stem cells derived from the human tooth germ (hTGSCs) are a heterogeneous cell population that can differentiate into osteogenic, neurogenic, and adipogenic lineages. The aim of this study was to compare the os...
Effect of Magnesium and Osteoblast Cell Presence on Hydroxyapatite Formation on (Ti,Mg)N Thin Film Coatings
Onder, Sakip; Calikoglu-Koyuncu, Ayse Ceren; Kose, Gamze Torun; Kazmanli, Kursat; Kök, Fatma Neşe; Urgen, Mustafa (Springer Science and Business Media LLC, 2017-07-01)
TiN and (Ti,Mg)N thin film coatings were deposited on Ti substrates by an arc-physical vapor deposition technique. The effect of cell presence on hydroxyapatite (HA) formation was investigated using surfaces with four diff...
Skeletal muscle patch engineering on synthetic and acellular human skeletal muscle originated scaffolds
Ay, Birol; KARAÖZ, Erdal; KESEMENLİ, CUMHUR CEVDET; KENAR, HALİME (2017-03-01)
The reconstruction of skeletal muscle tissue is currently performed by transplanting a muscle tissue graft from local or distant sites of the patient's body, but this practice leads to donor site morbidity in case of large...
Poly( amino acid)-based fibrous scaffolds modified with surface-pendant peptides for cartilage tissue engineering
Svobodova, Jana; Proks, Vladimir; Karabiyik, Ozge; Koyuncu, Ayse Ceren Calikoglu; Kose, Gamze Torun; Rypacek, Frantisek; Studenovska, Hana (Wiley, 2017-03-01)
In this study, fibrous scaffolds based on poly(gamma-benzyl-L-glutamate) (PBLG) were investigated in terms of the chondrogenic differentiation potential of human tooth germ stem cells (HTGSCs). Through the solution-assiste...
In vitro evaluation of PLLA/PBS sponges as a promising biodegradable scaffold for neural tissue engineering
Kanneci Altinisik, Irem Ayse; Kök, Fatma Neşe; Yucel, Deniz; KÖSE, GAMZE (The Scientific and Technological Research Council of Turkey, 2017-01-01)
In tissue engineering, the use of poly-L-lactic acid (PLLA)/polybutylene succinate (PBS) blend for the construction of scaffold is very limited. Moreover, polymeric sponges fabricated from PLLA/PBS have not been studied fo...
Micro-CT and nano-CT analysis of filling quality of three different endodontic sealers
Huang, Yan; ÇELİKTEN, BERKAN; Vasconcelos, Karla de Faria; Pinheiro Nicolielo, Laura Ferreira; Lippiatt, Nicholas; Büyüksungur, Arda; Jacobs, Reinhilde; ORHAN, KAAN (2017-01-01)
Objectives: To investigate voids in different root canal sealers using micro-CT and nano-CT, and to explore the feasibility of using nano-CT for quantitative analysis of sealer filling quality.
Biocompatibility of Accelerated Mineral Trioxide Aggregate on Stem Cells Derived from Human Dental Pulp.
Kulan, Pinar; Karabiyik, Ozge; KÖSE, GAMZE; Kargul, Betul (2016-02-01)
The aim of this study was to evaluate the effects of several additives on the setting time and cytotoxicity of accelerated-set mineral trioxide aggregate (MTA) on stem cells of human dental pulp. ProRoot white MTA (WMTA) (...
Bone Formation from Porcine Dental Germ Stem Cells on Surface Modified Polybutylene Succinate Scaffolds
Abay, Nergis; Gurel Pekozer, Gorke; Ramazanoglu, Mustafa; Kose, Gamze Torun (Hindawi Limited, 2016)
Designing and providing a scaffold are very important for the cells in tissue engineering. Polybutylene succinate (PBS) has high potential as a scaffold for bone regeneration due to its capacity in cell proliferation and d...
Behavior of mammalian cells on magnesium substituted bare and hydroxyapatite deposited (Ti, Mg) N coatings
Önder, Sakip; Calikoglu-Koyuncu, Ayşe Ceren; Kazmanli, Kürşat; Ürgen, Mustafa; Köse, Gamze Torun; Kök, Fatma Neşe (Elsevier BV, 2015-12-25)
TiN and (Ti,Mg)N thin film coatings were deposited on titanium substrates by using cathodic arc physical vapor deposition (arc-PVD) technique with magnesium contents of 0, 4.24 at% (low Mg) and 10.42 at% (high Mg). The pre...
Kemik Rejenerasyonunda Hızlı Prototip Teknolojisi
Kızıltay, Aysel (2015-01-01)
Kemik doku mühendisliği hasarlı kemiğin yenilenmesini amaçlar. Geleneksel üretim teknikleriyle geliştirilen iskele yapılar gözenek morfolojisinin ve yapısının kontrol edilememesi ve uyarlılığın olmaması gibi bazı kısıtlama...
Polybutylene Succinate (PBS) - Polycaprolactone (PCL) Blends Compatibilized with Poly(ethylene oxide)-block-poly( propylene oxide)-block-poly(ethylene oxide) (PEO-PPO-PEO) Copolymer for Biomaterial Applications
CAN, ERDE; Bucak, Seyda; Kinaci, Emre; Calikogly, Ayse Ceren; Kose, Gamze Torun (Informa UK Limited, 2014-01-01)
This study reports the preparation and characterization of Polybutylene Succinate (PBS)-Polycaprolactone (PCL) melt blends (10-40 wt.% PCL) in the presence of a compatibilizer, in order to explore their potential use as a ...
Bone response to biomimetic implants delivering BMP-2 and VEGF: An immunohistochemical study
RAMAZANOĞLU, Mustafa; Lutz, Rainer; Rusche, Philipp; Trabzon, Levent; Kose, Gamze Torun; Prechtl, Christopher; Schlegel, Karl Andreas (2013-12-01)
This animal study evaluated bone healing around titanium implant surfaces biomimetically coated with bone morphogenic protein-2 (BMP-2) and/or vascular endothelial growth factor (VEGF) by examining bone matrix proteins and...
Enhancing the value of nitrogen from rapeseed meal for microbial oil production
Kiran, Esra Uckun; Salakkam, Apilak; Trzcinski, Antoine P.; Bakir, Ufuk; Webb, Colin (2012-05-10)
Rapeseed meal, a major byproduct of biodiesel production, has been used as a low-cost raw material for the production of a generic microbial feedstock through a consolidated bioconversion process. Various strategies were t...