Department of Engineering Sciences

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Dicleli, Murat (179)
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Recent Submissions

Novel barium-doped-baghdadite incorporated PHBV-PCL composite fibrous scaffolds for bone tissue engineering Sadreddini, Sanaossadat; Jodati, Hossein; Evis, Zafer; Keskin, Dilek (2023-12-01) Bioceramic/polymer composites have dragged a lot of attention for treating hard tissue damage in recent years. In this study, we synthesized barium-doped baghdadite (Ba-BAG), as a novel bioceramic, and later developed fibr...
Development and validation of a digital twin of the human lower jaw under impact loading by using non-linear finite element analyses Demir, Osman; Uslan, Ibrahim; Büyük, Murat; SALAMCI, METİN UYMAZ (2023-12-01) Mandibular fractures are one of the most frequently observed injuries within craniofacial region mostly due to tumor-related problems and traumatic events, often related to non-linear effects like impact loading. Therefore...
Bioprinting of bioglass-alginate/carboxymethyl cellulose for bone tissue engineering Tahmasebifar, Aydin; Baran, Erkan Türker; Yilmaz, Bengi; Pazarçeviren, Ahmet Engin (2023-10-01) Bone regenerative medicine requires suitable substitutes that promote osteogenesis. Most of the bio-macromolecular hydrogels are promising because they are biocompatible and biodegradable, but their viscoelastic properties...
Boron nitride nanofiber/Zn-doped hydroxyapatite/polycaprolactone scaffolds for bone tissue engineering applications Turhan, Emine Ayşe; Akbaba, Sema; Tezcaner, Ayşen; Evis, Zafer (2023-05-01) In this study, Zn doped hydroxyapatite (Zn HA)/boron nitride nanofiber (BNNF)/poly-ε-caprolactone (PCL) composite aligned fibrous scaffolds are produced with rotary jet spinning (RJS) for bone tissue engineering applicatio...
Additive manufacturing of hexagonal lattice structures: Tensile tests and validation Ture, Mustafa Okan; Evis, Zafer; ÖZTÜRK, FAHRETTİN (2023-04-01) In this paper, different hexagonal lattice structures of the tensile test specimens were designed, manufactured by additive manufacturing, and tested in three different lengths. Moreover, flat shape tensile test specimens ...
3D porous bioceramic based boron-doped hydroxyapatite/baghdadite composite scaffolds for bone tissue engineering Jodati, Hossein; Evis, Zafer; Tezcaner, Ayşen; Alshemary, Ammar Z.; Motameni, Ali (2023-04-01) Making composite scaffolds is one of the well-known methods to improve the properties of scaffolds used in bone tissue engineering. In this study, novel ceramic-based 3D porous composite scaffolds were successfully prepare...
Diatom silica frustules-doped fibers for controlled release of melatonin for bone regeneration Deniz Dalgic, Ali; Atila, Deniz; Tezcaner, Ayşen; Gürses, Senih; Keskin, Dilek (2023-03-15) Sustained release of a bioactive agent from a tissue engineering scaffold is one of the most common strategies to improve regenerative potential of the construct. However, depending on the chemistry of the agent, achieving...
Nuclear Deformability of Breast Cells Analyzed from Patients with Malignant and Benign Breast Diseases Antmen, Ezgi; Ermiş Şen, Menekşe; Kuren, Ozgur; Beksac, Kemal; Irkkan, Cigdem; HASIRCI, Vasıf Nejat (2023-03-13) Breast cancer is a heterogeneous and dynamic disease, in which cancer cells are highly responsive to alterations in the microenvironment. Today, conventional methods of detecting cancer give a rather static image of the co...
Improvement of bioactivity with dual bioceramic incorporation to nanofibrous PCL scaffolds Altunordu, Gercem; Tezcaner, Ayşen; Evis, Zafer; Keskin, Dilek (2023-03-01) Bone tissue injuries, diseases or related clinical interventions require bone tissue engineering (BTE) approaches for regeneration of large bone defects, especially for compromised situations. Most BTE applications in lite...
1D reference V-S profiles compatible with ground-motion prediction equations developed for Turkey Ertuğrul, Zehra (2023-03-01) V-S30, time-averaged shear-wave velocity over the top 30 m of the site profile is the parameter that mainly governs site response functions in ground-motion prediction equations (GMPEs). Although the use of V-S30 as a main...
Effect of pile orientation on the fatigue performance of jointless bridge H-piles subjected to cyclic flexural strains Karalar, Memduh; Dicleli, Murat (2023-02-01) This paper explores the effect of pile orientation on the low cycle fatigue (LCF) performance of steel H–piles (SPs) at jointless bridge (JB) abutments via experimental testing and finite element simulation. The experiment...
Comparative seismic behavior assessment of a new damper-equipped and conventional chevron-braced frames Milani, Ali Salem; Dicleli, Murat (2023-02-01) This paper presents the results of experimental studies performed on three 1/3-scale steel building frames for comparative assessment of the cyclic behavior of a Chevron frame equipped with a newly-developed damper, THDF (...
Injectable methacrylated gelatin/thiolated pectin hydrogels carrying melatonin/tideglusib-loaded core/shell PMMA/silk fibroin electrospun fibers for vital pulp regeneration Atila, Deniz; Keskin, Dilek; Lee, Yuan-Ling; Lin, Feng-Huei; Hasirci, Vasif; Tezcaner, Ayşen (2023-02-01) Use of injectable hydrogels attract attention in the regeneration of dental pulp due to their ability to fill non-uniform voids such as pulp cavities. Here, gelatin methacrylate/thiolated pectin hydrogels (GelMA/PecTH) car...
Synthesis and characterization of pure and Mg, Cu, Ag, and Sr doped calcium-deficient hydroxyapatite from brushite as precursor using the dissolution-precipitation method Lakrat, Mohammed; Jodati, Hossein; Mejdoubi, El Miloud; Evis, Zafer (2023-01-01) Calcium-deficient hydroxyapatite (CDHA) is an attractive biomaterial for medical applications due to its similarity with the mineral part of bones. This study presents, for the first time, the preparation of CDHA form brus...
Alginate/gelatin/boron-doped hydroxyapatite-coated Ti implants: in vitro and in vivo evaluation of osseointegration Pazarçeviren, Ahmet Engin; Evis, Zafer; Dikmen, Tayfun; Altunbaş, Korhan; Yaprakçı, Mustafa V.; Keskin, Dilek; Tezcaner, Ayşen (2023-01-01) In this study, boron-doped hydroxyapatite (BHT)-loaded alginate/gelatin-based (A/G) hydrogel coating on Ti was fabricated to support bone integration through triggering osteoinduction, vascularization and immunomodulation....
Machining parameters and distortion analyses in end milling of AA2050 and AA7050 Ates, Elvan; Evis, Zafer; ÖZTÜRK, FAHRETTİN (2023-01-01) The machining of high-strength-low-density materials such as AA2050-T84 and AA7050-T7451 has become one of the most important focuses in the development of the aerospace industry. AA7050-T7451 that shows good fatigue resis...
Local application of gingiva-derived mesenchymal stem cells on experimental periodontitis in rats Balaban, Yunus Emre; Akbaba, Sema; Bozkurt, Serife Buket; BÜYÜKSUNGUR, ARDA; Akgun, E. Ece; GÖNEN, ZEYNEP BURÇİN; Salkin, Hasan; Tezcaner, Ayşen; Hakki, Sema S. (2023-01-01) Background: Stem cell-based approaches in regenerative periodontal therapy have been used in different experimental models. In this study, the effect of local application of gingival mesenchymal stem cells (GMSC) in fibroi...
Fibroin reinforced, strontium-doped calcium phosphate silicate cements for bone tissue engineering applications Işık, Gülhan; Pazarçeviren, Ahmet Engin; Evis, Zafer; Tezcaner, Ayşen (2023-01-01) Calcium phosphate silicate cements (CPSCs) have been developed to overcome problems like high acidity due to presence of brushite and high temperatures evolving as polymethyl methacrylate (PMMA) cements cure at surgery sit...
SENSITIVITY ANALYSIS FOR DERIVATION OF 1D VS PROFILES USING INVERSE QUARTER-WAVELENGTH THEORY Ozisin, Mehmet; Ertuğrul, Zehra (2023-01-01) It is possible to convert median response spectra estimated based on a selected Ground-motion Prediction Equation (GMPE) to its corresponding Fourier amplitude spectrum (FAS) by using the inverse vibration theory (IRVT). T...
Nickel titanium alloys as orthodontic archwires: A narrative review Uysal, Idil; Yilmaz, Bengi; Atilla, Aykan Onur; Evis, Zafer (2022-12-01) Nickel-titanium (NiTi) archwires have been widely used in orthodontic treatments at the aligning and leveling step which is the initial stage of the treatment. This review presents the concepts related to NiTi archwires fr...

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