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Conceptual integration within the context of stem education Yiğit Dönmezoğulları, Ümran; Öztürk, Gökhan; Department of Science Education (2026-7) The ability to integrate knowledge and ways of thinking across disciplines has become a central goal of contemporary STEM education. Despite this emphasis, limited research has examined how students from different educational programmes integrate disciplinary knowledge when responding to real-world problems. This study investigated differences in conceptual integration between students educated within the International Baccalaureate (IB) Diploma Programme and the Turkish Ministry of National Education (MoNE...
A numerical study on lateral bracing of steel moment resisting frame beams Saltık, Heval; Topkaya, Cem; Department of Civil Engineering (2026-8-12) Beams of special moment frames (SMFs) are expected to sustain large inelastic rotations under seismic loading, while local buckling and lateral-torsional buckling may cause strength degradation. This thesis numerically investigates the cyclic lateral-torsional buckling behavior of stiffened and unstiffened I-shaped SMF beams under different lateral restraint conditions and evaluates the adequacy of the AISC 341-16 lateral bracing requirement. After verifying the finite element modeling approach, beams with ...
Machine learning-based drug response prediction in colorectal cancer with reduced features Coşgun, Mert; Acar, Ahmet; Department of Molecular Biology and Genetics (2026-7-29) The heterogeneous nature of colorectal cancer leads to significant variations in patients’ response to treatment processes. Even though various machine learning models have been implemented to predict the response to anticancer drug treatments, relying on complex and high-dimensional data limits their interpretability and real-world applications. In this thesis, various pipelines were developed with reduced features, integrating colorectal cancer cell lines’ gene expression and mutation profiles data with m...
CALCULATIONS FOR HAZARDOUS AREA CLASSIFICATION IN POTENTIAL EXPLOSIVE ATMOSPHERES KAYA, Çağatay; Karakaş, Gürkan; Department of Occupational Health and Safety (2026-8-06) This study analysed the applicability, scope, outputs, and limitations of methods used for explosion protection. Its principal analytical basis was the comparison of IEC/ATEX-based hazardous area classification results with consequence-screening outputs generated by RAST software. HAZID and an EN 16985-based spray-process assessment complemented these approaches where specific hazard mechanisms and process conditions could not be represented adequately. The study aimed to identify fire- and explosion-relate...
A medieval city in transformation: A GIS-based documentation, identification, and assessment of the Byzantine heritage in Trebizond (Trabzon) Sur, Selin; Serin, Ufuk; Conservation of Cultural Heritage in Department of Architecture (2026-7-30) Trebizond (modern Trabzon) is one of the longest continuously inhabited cities on the Black Sea coast of Türkiye, with origins dating back to at least the Hellenistic period (330–30 BCE). It is also among the rare urban centers that seamlessly transitioned through the ‘Dark Ages’ (7th–9th centuries) into modern times without major settlement interruption. After the capture of Constantinople (Istanbul) by the Fourth Crusade in 1204, the city became the capital of one of the three Byzantine splinter states, n...

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